--- title: "HGH Peptide UK - Compare Prices from 21 Suppliers - PeptideSupermarket®" description: "Compare HGH prices from 21 UK suppliers, from £14.58. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.uk/peptide/hgh" site: "PeptideSupermarket®" country: "United Kingdom" --- [Home](https://peptidesupermarket.co.uk) › [Peptides](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) › HGH Search # HGH Price Comparison Live prices from 21 UK suppliers, from £14.58, compared side by side so you never overpay. [Growth hormone axis](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) We compare prices & may earn a commission. [Full disclosure](https://peptidesupermarket.co.uk/disclosure). Best Price £19.99 Average £35.49 Highest £79.99 You Could Save 75% 8 results 5mg Compare 8 prices for HGH. Cheapest: £19.99. Average: £35.49. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | 95 Confidence [Ultra Peptides](https://peptidesupermarket.co.uk/suppliers/ultra-peptides-uk) ★★★★★ 5.0 (13) HGH 5mg | £39.99 | £8.00/mg | In Stock | Free | Lab Tested | — | Visit | | | 95 Confidence [BioPlex Peptides](https://peptidesupermarket.co.uk/suppliers/bioplex-peptides) ★★★★★ 5.0 (1) HGH | £32.99 | £6.60/mg | In Stock | Free | Lab Tested | — | Visit | | | 50 Confidence [XL Peptides](https://peptidesupermarket.co.uk/suppliers/xl-peptides) Best ★★★★★ 5.0 (1) HGH 5mg | £19.99 | £4.00/mg | In Stock | Free | Lab Tested | — | Visit | | | 50 Confidence [Peptagenix Peptides](https://peptidesupermarket.co.uk/suppliers/peptagenix-peptides) HGH 5mg | £24.95 | £4.99/mg | In Stock | Free | Lab Tested | — | Unavailable | | | 50 Confidence [Syntech](https://peptidesupermarket.co.uk/suppliers/syntech) HGH 5mg | £27.99 | £5.60/mg | In Stock | Free | Lab Tested | — | Visit | | | 50 Confidence [Research Peptides](https://peptidesupermarket.co.uk/suppliers/research-peptides) HGH 5mg | £29.00 | £5.80/mg | In Stock | Free | Lab Tested | — | Visit | | | 50 Confidence [El Toro](https://peptidesupermarket.co.uk/suppliers/el-toro) HGH 5mg | £29.00 | £5.80/mg | In Stock | Free | Lab Tested | — | Visit | | | 50 Confidence [Peptides Distro](https://peptidesupermarket.co.uk/suppliers/peptides-distro) HGH 5mg | £79.99 | £16.00/mg | In Stock | Free | — | — | Unavailable | More ways to compare HGH Different views of the same live UK pricing, tuned for how you like to shop. [Best HGH Prices Best prices ranked](https://peptidesupermarket.co.uk/best-hgh-prices) [Cheapest HGH Prices Cheapest suppliers compared](https://peptidesupermarket.co.uk/cheapest-hgh-prices) [Where to Buy HGH Full buyer's guide](https://peptidesupermarket.co.uk/where-to-buy-hgh) [Buy HGH Online UK Cheap Today's hottest deals](https://peptidesupermarket.co.uk/buy-hgh-online-uk-cheap) [HGH Price Comparison Live price dashboard](https://peptidesupermarket.co.uk/hgh-price-comparison) [HGH UK Supplier Verified UK supplier directory](https://peptidesupermarket.co.uk/hgh-uk-supplier) [HGH For Sale Browse listings for sale](https://peptidesupermarket.co.uk/hgh-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.uk/disclosure). ## HGH Profile Fda Approved FDA Approved Human Growth Hormone | Somatropin ### Overview Human Growth Hormone (HGH/Somatropin) is a 191-amino acid polypeptide hormone FDA-approved for pediatric and adult growth hormone deficiency, HIV-associated wasting, and other conditions. It provides both direct and indirect (IGF-1 mediated) anabolic effects. ### Mechanism of Action Binds to GH receptors on target tissues, triggering JAK2-STAT5 signaling pathway. Direct effects include lipolysis, protein synthesis, and metabolic regulation. Indirect effects via IGF-1 promote growth and anabolism. Half-life ~3 hours subcutaneously. ### Key Benefits - Improved body composition (increased lean mass, decreased fat) - Enhanced bone mineral density - Improved lipid profile - Increased exercise capacity - Better quality of life and mood - Skin, hair, and nail improvements - Enhanced recovery and healing ### Quick Stats Typical Dose 1-4 IU daily (0.33-1.33mg); start low and titrate up Frequency Once daily or split into 2 doses (morning and evening) Cycle Duration 3-6+ months or ongoing for medical GHD Storage Lyophilized: Room temperature. Reconstituted: 2-8°C, use within 14-28 days ## Molecular Information Molecular Weight 22,124 Da Length 191 amino acids Type Single-chain polypeptide with two disulfide bridges Half-Life 3-4 hours (SC), 20-30 minutes (IV) ### Modifications 4 cysteine residues forming 2 intrachain disulfide bonds Bioidentical to natural pituitary HGH Recombinant via E. coli DNA technology ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Growth Hormone Deficiency Body Composition Anti-Aging ## Dosing Protocols ### injectable Subcutaneous injection is the only effective route. Morning fasted injection maximizes fat-burning potential; evening mimics natural nocturnal GH pulse. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Medical GHD (Starting) | 0.15-0.3mg/day (0.5-1 IU) | Once daily | SubQ | | Medical GHD (Maintenance) | 0.4-0.8mg/day (1.2-2.4 IU) | Once daily | SubQ | | Anti-Aging/Wellness | 1-2 IU/day (0.33-0.67mg) | Once daily | SubQ | | Body Recomposition | 2-4 IU/day (0.67-1.33mg) | Once or twice daily | SubQ | | Performance (Higher Risk) | 4-8 IU/day (1.33-2.67mg) | Split twice daily | SubQ | #### Key Tips - Abdomen (most common), thigh, upper arm injection sites - Rotate sites to prevent lipohypertrophy - Morning fasted or evening dosing Reconstitution Instructions ## Peptide Interactions #### Insulin Monitor HGH decreases insulin sensitivity; may require increased insulin doses in diabetics. #### IGF-1/IGF-1 LR3 Monitor Synergistic but caution: enhanced effects with increased hypoglycemia and side effect risk. #### Thyroid Hormones (T3/T4) Monitor Increases T4 to T3 conversion; unmasks hypothyroidism in 36-47% of patients. #### CJC-1295 Synergistic GHRH analog can enhance effects though may be redundant with exogenous HGH. #### Ipamorelin Synergistic Ghrelin mimetic works via different pathway. #### GHRP-6/GHRP-2 Synergistic Enhances natural pulsatile release. #### Cortisol/Hydrocortisone Monitor Can unmask cortisol deficiency; replacement should precede HGH. #### Testosterone Synergistic Commonly combined in hormone replacement therapy. #### Metformin Monitor May manage insulin resistance; may reduce IGF-1 levels. #### Semaglutide/Tirzepatide Compatible GLP-1 agonists help manage insulin resistance during HGH therapy. ## What to Expect Week 1-2 Improved sleep quality, increased energy, possible water retention and joint stiffness Week 2-4 Enhanced exercise recovery, skin improvement, possible carpal tunnel symptoms Month 1-2 Noticeable fat loss (especially abdominal), improved skin elasticity and texture Month 2-3 Continued fat loss, lean mass improvements, hair/nail growth, reduced recovery time Month 3-6 Significant body composition changes, improved bone density, sustained energy/well-being Long-term Maintained benefits; effects diminish weeks-months after discontinuation ## Side Effects & Safety #### Common Side Effects - Water retention and fluid accumulation - Joint pain and stiffness - Carpal tunnel syndrome (usually resolves with dose reduction) - Headaches - Numbness/tingling in hands #### Monitoring - Blood glucose - HGH causes insulin resistance and can unmask diabetes - Thyroid function - can unmask hypothyroidism; may require T4 supplementation - IGF-1 levels to assess dosing adequacy - Intracranial pressure if headaches develop #### Stop Signs - Severe or worsening carpal tunnel symptoms - Signs of diabetes (increased thirst, frequent urination, blurred vision) - Severe edema (facial, hand, or feet swelling) - Severe joint/muscle pain unresponsive to dose reduction - New lumps, masses, or rapidly growing moles - Severe headaches or vision changes - Signs of allergic reaction - Gynecomastia (breast tissue growth in males) - Hypothyroid symptoms (fatigue, weight gain, cold intolerance) #### Contraindications - Active cancer (may accelerate tumor growth) - Acute critical illness (increased mortality in ICU patients) - Closed epiphyses in children (for growth promotion) - Pregnancy/breastfeeding ## Quality Checklist #### Good Signs - White to off-white lyophilized powder or solid cake (not liquid/collapsed) - Crystal clear reconstituted solution with no particles - Intact vacuum in sealed vial (resistance when inserting needle) - Pharmaceutical grade with certificate of analysis (Genotropin, Norditropin, Humatrope preferred) #### Warning Signs - Generic/underground lab products have highly variable quality and potency - Common counterfeits exist; third-party testing recommended #### Bad Signs - Cloudy, discolored, or particles visible indicates degradation - Powder appears melted or stuck to vial (improper storage) - Yellow/brown coloring ## Research & References ### Latest Research 2023 #### Long-Acting Somatropin Formulations FDA Sogroya and Skytrofa FDA-approved for improved once-weekly dosing convenience. ### Key References 1. 2020 #### KIMS Long-Term Safety Study 15,809 patients, mean 5.3 years follow-up. Largest long-term safety study showing de novo cancer incidence comparable to general population (SIR 0.92). 2. 2018 #### Long-term Efficacy and Safety in Adult GHD Systematic review demonstrating improvements in body composition, muscle strength, quality of life, bone mass/density, and lipoprotein patterns. 3. 2016 #### Effects on Morbidity - Systematic Review Demonstrated positive effects on cardiovascular surrogate markers and bone metabolism. 4. 2015 #### GH-Thyroid Hormone Interaction Study GH replacement unmasks central hypothyroidism in 36-47% of apparently euthyroid patients. [Search PubMed for HGH](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22HGH%22%20OR%20%22Human%20Growth%20Hormone%20Fragment%20176-191%22%20OR%20%22Somatropin%22%20OR%20%22Somatotropin%22%20OR%20%22rhGH%22%20OR%20%22Recombinant%20Human%20Growth%20Hormone%22%29) --- *Add `.md` to any page URL on peptidesupermarket.co.uk for its Markdown version. Index of the site: https://peptidesupermarket.co.uk/llms.txt - full text: https://peptidesupermarket.co.uk/llms-full.txt.*