--- title: "Mots-C Peptide UK - Compare Prices from 238 Suppliers - PeptideSupermarket®" description: "Compare Mots-C prices from 238 UK suppliers, from £7.49. Find the cheapest deals, read reviews and save money." url: "https://peptidesupermarket.co.uk/peptide/mots-c" site: "PeptideSupermarket®" country: "United Kingdom" --- [Home](https://peptidesupermarket.co.uk) › [Peptides](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) › Mots-C Search # Mots-C Price Comparison Live prices from 238 UK suppliers, from £7.49, compared side by side so you never overpay. [Skin & cellular longevity research](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) Prices checked 2 hours ago We compare prices & may earn a commission. Includes a featured placement — not an endorsement. [Full disclosure](https://peptidesupermarket.co.uk/disclosure). Best Price £13.99 Average £32.66 Highest £199.99 You Could Save 93% 196 results 10mg Featured Supplier [UK SARMs](https://peptidesupermarket.co.uk/suppliers/uk-sarms) ★★★★★ [5.0 reviews](https://peptidereview.co.uk/review/uksarms.com) Mots-C 10mg In Stock 10mg Lab Tested 95 Confidence £49.99 FREE delivery View Deal Compare 196 prices for Mots-C. Cheapest: £13.99. Average: £32.66. | Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | 95 Confidence [PS Labs](https://peptidesupermarket.co.uk/suppliers/ps-labs) ★★★★★ 5.0 (26) Mots-C | £25.00 | £2.50/mg | In Stock | Free over £100 | Lab Tested | — | Visit | | | 95 Confidence [Biohack Peptides](https://peptidesupermarket.co.uk/suppliers/biohack-peptides) ★★★★★ 4.9 (88) Mots-C | £18.99 | £1.90/mg | In Stock | Free | Lab Tested | — | Visit | | | 95 Confidence [Owsa Labs](https://peptidesupermarket.co.uk/suppliers/owsa-labs) ★★★★★ 5.0 (15) Mots-C | £34.99 | £3.50/mg | In Stock | Free | Lab Tested | — | Visit | | | 95 Confidence [Zentra Peptides](https://peptidesupermarket.co.uk/suppliers/zentra-peptides) ★★★★★ 5.0 (11) Mots-C | £21.99 | £2.20/mg | In Stock | Free over £100 | Lab Tested | — | Visit | | | 95 Confidence [Ultra Peptides](https://peptidesupermarket.co.uk/suppliers/ultra-peptides-uk) ★★★★★ 5.0 (13) Mots-C 10mg | £19.99 | £2.00/mg | In Stock | Free | Lab Tested | — | Visit | | | 95 Confidence [Molexa](https://peptidesupermarket.co.uk/suppliers/molexa) ★★★★★ 5.0 (10) Mots-C | £27.99 | £2.80/mg | In Stock | £5.50 | Lab Tested | — | Visit | | | 95 Confidence [Alpha Peptides®](https://peptidesupermarket.co.uk/suppliers/alpha-peptides) ★★★★★ 5.0 (4) Mots-C | £21.00 | £2.10/mg | In Stock | Free over £100 | Lab Tested | — | Visit | | | 95 Confidence [BioPlex Peptides](https://peptidesupermarket.co.uk/suppliers/bioplex-peptides) ★★★★★ 5.0 (1) Mots-C 10mg | £29.99 | £3.00/mg | In Stock | Free | Lab Tested | — | Visit | | | 95 Confidence [Midshire Labs](https://peptidesupermarket.co.uk/suppliers/midshire-labs) Mots-C | £23.00 | £2.30/mg | In Stock | Free over £50 | Lab Tested | — | Visit | | | 94 Confidence [Elite peptides](https://peptidesupermarket.co.uk/suppliers/elite-peptides) ★★★★★ 5.0 (46) Mots-C 10mg | £23.39 | £2.34/mg | In Stock | Free over £60 | Lab Tested | — | Visit | | | 92 Confidence [D&L Peptides](https://peptidesupermarket.co.uk/suppliers/dl-peptides) Mots-C 10mg | £20.00 | £2.00/mg | In Stock | Free | Lab Tested | — | Unavailable | | | 92 Confidence [Raven Peptides](https://peptidesupermarket.co.uk/suppliers/raven-peptides) ★★★★★ 5.0 (8) Mots-C 10mg | £18.99 | £1.90/mg | In Stock | Free | Lab Tested | — | Visit | | | 90 Confidence [Cobalt Peptides](https://peptidesupermarket.co.uk/suppliers/cobalt-peptides) ★★★★★ 5.0 (19) Mots-C | £21.95 | £2.20/mg | In Stock | Free over £75 | Lab Tested | — | Visit | | | 90 Confidence [Apex Biolabs](https://peptidesupermarket.co.uk/suppliers/apex-biolabs) ★★★★★ 5.0 (20) MOTS-C 10mg \| UK Research Peptide \| & 3ml Bac water - | £25.00 | £2.50/mg | In Stock | Free | Lab Tested | — | Visit | | | 88 Confidence [Cedar Peptides](https://peptidesupermarket.co.uk/suppliers/cedar-peptides) ★★★★★ 5.0 (1) Mots-C 10mg | £23.95 | £2.40/mg | In Stock | Free over £100 | Lab Tested | — | Visit | | | 88 Confidence [Adria](https://peptidesupermarket.co.uk/suppliers/adria) Mots-C 10mg | £43.29 | £4.33/mg | In Stock | Free | — | — | Visit | | | 87 Confidence [PeptideStock](https://peptidesupermarket.co.uk/suppliers/peptidestockcouk) ★★★★★ 4.6 (14) Mots-C | £18.99 | £1.90/mg | Out of Stock | Free over £75 | Lab Tested | — | Visit | | | 87 Confidence [Revial Labs](https://peptidesupermarket.co.uk/suppliers/revial-labs) Mots-C | £32.99 | £3.30/mg | In Stock | Free over £150 | Lab Tested | — | Unavailable | | | 85 Confidence [Precision Peptides](https://peptidesupermarket.co.uk/suppliers/precision-peptides) ★★★★★ 5.0 (9) Mots-C 10mg | £22.99 | £2.30/mg | In Stock | Free | Lab Tested | — | Visit | | | 85 Confidence [Fat Pig Peptides](https://peptidesupermarket.co.uk/suppliers/fat-pig-peptides) Mots-C | £22.99 | £2.30/mg | In Stock | £5.15 | Lab Tested | — | Visit | | | 82 Confidence [Arma Peptides](https://peptidesupermarket.co.uk/suppliers/arma-peptides-2) ★★★★★ 5.0 (2) Mots-C | £23.00 | £2.30/mg | In Stock | Free | — | — | Visit | | | 82 Confidence [Arma Peptides](https://peptidesupermarket.co.uk/suppliers/arma-peptides-2) ★★★★★ 5.0 (2) Mots-C Pen | £70.00 | £7.00/mg | In Stock | Free | — | — | Visit | | | 81 Confidence [SPX Labs](https://peptidesupermarket.co.uk/suppliers/spx-labs) Mots-C 10mg | £16.99 | £1.70/mg | In Stock | Free over £75 | Lab Tested | — | Visit | | | 80 Confidence [Optimus Labs](https://peptidesupermarket.co.uk/suppliers/optimus-labs) Mots-C | £23.50 | £2.35/mg | In Stock | Free over £30 | Lab Tested | — | Visit | | | 80 Confidence [Raccoon Peptides](https://peptidesupermarket.co.uk/suppliers/raccoon-peptides) ★★★★★ 5.0 (1) Mots-C 10mg | £17.49 | £1.75/mg | In Stock | Free | Lab Tested | — | Unavailable | Showing 25 of 195 listings Show more suppliers Loading More ways to compare Mots-C Different views of the same live UK pricing, tuned for how you like to shop. [Best Mots-C Prices Best prices ranked](https://peptidesupermarket.co.uk/best-mots-c-prices) [Cheapest Mots-C Prices Cheapest suppliers compared](https://peptidesupermarket.co.uk/cheapest-mots-c-prices) [Where to Buy Mots-C Full buyer's guide](https://peptidesupermarket.co.uk/where-to-buy-mots-c) [Buy Mots-C Online UK Cheap Today's hottest deals](https://peptidesupermarket.co.uk/buy-mots-c-online-uk-cheap) [Mots-C Price Comparison Live price dashboard](https://peptidesupermarket.co.uk/mots-c-price-comparison) [Mots-C UK Supplier Verified UK supplier directory](https://peptidesupermarket.co.uk/mots-c-uk-supplier) [Mots-C For Sale Browse listings for sale](https://peptidesupermarket.co.uk/mots-c-for-sale) Compare another peptide Search PeptideSupermarket® compares prices but doesn't sell products. More All purchases are made directly from third-party suppliers; your relationship is solely with them. We accept no liability for the quality, purity, or legality of any products listed. We may earn a commission when you click through to a supplier and make a purchase. This does not affect pricing information displayed. By using this site you accept responsibility for ensuring purchases comply with applicable laws in your jurisdiction. [Read our full disclosure](https://peptidesupermarket.co.uk/disclosure). ## Mots-C Profile Well Studied Mitochondrial-Derived Peptide | Metabolic Regulator ### Overview MOTS-c is a mitochondrial-derived peptide that operates as a mitohormone through the Folate-AICAR-AMPK pathway. Under metabolic stress, it translocates to the nucleus to bind stress-response transcription factors (NRF2, ATF1/ATF7), regulating genes involved in metabolism and cellular adaptation. ### Mechanism of Action Inhibits the folate cycle leading to AMPK activation. Under metabolic stress, translocates to nucleus to bind stress-response transcription factors, regulating genes involved in metabolism, insulin sensitivity, and cellular adaptation. ### Key Benefits - Enhanced insulin sensitivity (~30% improvement) - Improved glucose metabolism and tolerance - AMPK pathway activation - Mitochondrial function optimization - Exercise performance enhancement (12-15% improvement) - Potential lifespan extension (6.4% median increase in mice) ### Quick Stats Typical Dose Start 5mg daily, increase to 10-15mg based on goals Frequency Daily for metabolic support, or 3x weekly for anti-aging Cycle Duration 4-12 weeks depending on goals Storage Refrigerate reconstituted solution at 2-8°C, use within 14 days ## Molecular Information Molecular Weight 2,174.6 Da Length 16 amino acids Type Mitochondrial-derived peptide (MDP) Half-Life ~30 minutes ### Amino Acid Sequence One-letter: `MRWQEMGYIFYPRKLR` Met 1 Methionine Position 1 Arg 2 Arginine Position 2 Trp 3 Tryptophan Position 3 Gln 4 Glutamine Position 4 Glu 5 Glutamic Acid Position 5 Met 6 Methionine Position 6 Gly 7 Glycine Position 7 Tyr 8 Tyrosine Position 8 Ile 9 Isoleucine Position 9 Phe 10 Phenylalanine Position 10 Tyr 11 Tyrosine Position 11 Pro 12 Proline Position 12 Arg 13 Arginine Position 13 Lys 14 Lysine Position 14 Leu 15 Leucine Position 15 Arg 16 Arginine Position 16 N-terminus C-terminus Hydrophobic Polar Positive (+) Negative (-) Modified ### Modifications Encoded by mitochondrial DNA (MT-RNR1 gene) within 12S rRNA ## Research Indications The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research. Metabolic Anti-Aging Exercise Performance ## Dosing Protocols ### injectable Subcutaneous injection is the primary route. Optimal administration is morning before exercise. AMPK activation occurs within 30 minutes. | Goal | Dose | Frequency | Route | | --- | --- | --- | --- | | Metabolic health | 5-10mg | Once daily | SubQ | | Anti-aging protocol | 15mg | 3x weekly | SubQ | | Exercise performance | 10-15mg | Pre-workout | SubQ | | Conservative start | 5mg | Once daily | SubQ | #### Key Tips - Morning before exercise is optimal timing - AMPK activation within 30 minutes - Use within 14 days of reconstitution Reconstitution Instructions ## Peptide Interactions #### Metformin Monitor Both activate AMPK; monitor for additive hypoglycemic effects. #### NAD+ Precursors Synergistic Complementary mitochondrial enhancement through different pathways. #### Growth Hormone Peptides Compatible Different mechanisms allow safe combination. #### Berberine Monitor Both are AMPK activators; monitor for additive effects. #### Resveratrol Synergistic Complementary SIRT1/AMPK activation pathways. #### Diabetes Medications Monitor May require dose adjustments to prevent hypoglycemia. ## What to Expect Week 1-2 AMPK pathway activation; initial glucose tolerance improvements Week 2-4 Enhanced exercise capacity; improved insulin sensitivity Week 4-8 Sustained metabolic benefits; potential body composition changes Week 8-12 Maximum mitochondrial function enhancement; metabolic flexibility ## Side Effects & Safety #### Common Side Effects - Generally well-tolerated in animal studies with minimal side effects - Mild injection site reactions (redness, swelling) #### Monitoring - Blood glucose if using diabetes medications - Monitor for hypoglycemia symptoms - Start conservatively (5-10mg) - Appropriate medical supervision recommended #### Stop Signs - Severe allergic reactions or anaphylaxis - Recurrent hypoglycemia (<50 mg/dL) - Persistent severe injection site reactions - Unexplained weight loss >10% of baseline #### Contraindications - Pregnancy or breastfeeding - WADA prohibited substance (banned for athletic competition) - Limited long-term human safety data ## Quality Checklist #### Good Signs - White to off-white powder with uniform appearance indicating proper storage - Clear, colorless solution without particles after reconstitution - Sequence verification (MRWQEMGYIFYPRKLR) with CoA >95% purity by RP-HPLC #### Warning Signs - Limited human clinical data - start conservatively - WADA banned substance - not for competitive athletes #### Bad Signs - Discolored powder or solution - Cloudy solution after reconstitution - No certificate of analysis available ## Research & References ### Latest Research 2025 #### Age-Related Macular Degeneration Study Ophthalmology Research Dose-dependent protective effects on retinal cells in AMD models. ### Key References 1. 2015 #### [The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance.](https://pubmed.ncbi.nlm.nih.gov/25738459/) PubMed Cell metabolism · Lee C, Zeng J, Drew BG, Sallam T, Martin-Montalvo A, Wan J, Kim SJ, Mehta H, Hevener AL, de Cabo R, Cohen P This foundational study identified MOTS-c as a peptide encoded within mitochondrial 12S rRNA and reported effects on cellular folate-cycle metabolism, AMPK signaling, body-weight gain, and insulin-sensitivity measures in mouse metabolic models. 2. 2021 #### [MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis.](https://pubmed.ncbi.nlm.nih.gov/33473109/) PubMed Nature communications · Reynolds JC, Lai RW, Woodhead JST, Joly JH, Mitchell CJ, Cameron-Smith D, Lu R, Cohen P, Graham NA, Benayoun BA, Merry TL, Lee C This study reported that circulating MOTS-c is induced by exercise and characterized age-related skeletal-muscle and physical-performance phenotypes in animal and human exercise contexts. 3. 2018 #### [Circulating MOTS-c levels are decreased in obese male children and adolescents and associated with insulin resistance.](https://pubmed.ncbi.nlm.nih.gov/29691953/) PubMed Pediatric diabetes · Du C, Zhang C, Wu W, Liang Y, Wang A, Wu S, Zhao Y, Hou L, Ning Q, Luo X This observational study measured circulating MOTS-c in obese male children and adolescents and reported associations with insulin-resistance-related clinical variables. [Search PubMed for Mots-C](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Mots-C%22%20OR%20%22Mitochondrial%20Open%20Reading%20Frame%20of%20the%2012S%20rRNA-c%20%28C%29%22%20OR%20%22Mitochondrial%20Open%20Reading%20Frame%20of%20the%2012S%20rRNA-c%22%29) Research Library ## Mots-C research & guides Plain-English guides and study summaries from published literature. [View all 8](https://peptidesupermarket.co.uk/research/peptide/mots-c) ![Common Reasons People Struggle With MOTS-c](https://peptidesupermarket.co.uk/storage/2574/conversions/01KN9D946A7C7ME4P5TEFWB3K3-thumbnail.jpg) Guides 4 min ### Common Reasons People Struggle With MOTS-c From unrealistic expectations to poor support, several patterns appear again and again when people say MOTS-c made them feel worse. Read article [Common Reasons People Struggle With MOTS-c](https://peptidesupermarket.co.uk/research/common-reasons-people-struggle-with-mots-c) ![MOTS-c and Metabolic Flexibility: Why the Transition Can Feel Rough](https://peptidesupermarket.co.uk/storage/2573/conversions/01KN9D60ZD6EAJ00W8QE2510X1-thumbnail.jpg) Guides 6 min ### MOTS-c and Metabolic Flexibility: Why the Transition Can Feel Rough MOTS-c is often explored for mitochondrial signalling, but the shift from one energy pattern to another may not feel smooth at the start. Read article [MOTS-c and Metabolic Flexibility: Why the Transition Can Feel Rough](https://peptidesupermarket.co.uk/research/mots-c-and-metabolic-flexibility-why-the-transition-can-feel-rough) ![Why MOTS-c May Cause Fatigue Before Energy Improves](https://peptidesupermarket.co.uk/storage/2572/conversions/01KN9D283C6PCZ9MRKZ8EZZ6XP-thumbnail.jpg) Guides 5 min ### Why MOTS-c May Cause Fatigue Before Energy Improves Some people report feeling more tired when they start MOTS-c. Here is the cleaner explanation for why that may happen and what the discussion usually centres on. Read article [Why MOTS-c May Cause Fatigue Before Energy Improves](https://peptidesupermarket.co.uk/research/why-mots-c-may-cause-fatigue-before-energy-improves) ![MOTS-C: the mitochondrial signal your body is missing](https://peptidesupermarket.co.uk/storage/128/conversions/01KH6SGJPQ069DSDMBPMCWGC5X-thumbnail.jpg) Guides 7 min ### MOTS-C: the mitochondrial signal your body is missing Do you remember in middle school when we learned that mitochondria are the powerhouse of the cell? Well, as you age, your body produces less of a peptide that tells those mitochondria how to burn fat and use energy efficiently. And MOTS-C might be the signal your mitochondria have been missing. Read article [MOTS-C: the mitochondrial signal your body is missing](https://peptidesupermarket.co.uk/research/mots-c-the-mitochondrial-signal-your-body-is-missing) ![How to mix, handle, and store peptides so you don’t ruin them](https://peptidesupermarket.co.uk/storage/120/conversions/01KH6Q2RWV79PH2D5SEMVAFBP9-thumbnail.jpg) Guides 6 min ### How to mix, handle, and store peptides so you don’t ruin them How to mix, handle, and store peptides so you don’t ruin them If you’re new to peptides, the confusing part isn’t the vial of powder — it’s the fact that there are two different rulebooks: Before reconstitution (dry, lyophilized powder): you’re protecting it from moisture After reconstitution (liquid): you’re managing two clocks at once: Microbial safety Chemical stability (potency) Once you understand why those rules exist, you stop guessing and you stop accidentally degrading your product. Read article [How to mix, handle, and store peptides so you don’t ruin them](https://peptidesupermarket.co.uk/research/how-to-mix-handle-and-store-peptides-so-you-dont-ruin-them) ![Why most people use MOTS-C wrong — and how to run it the way it’s designed to work](https://peptidesupermarket.co.uk/storage/119/conversions/01KH6PRSCKA3PYK087R1RFBYEA-thumbnail.jpg) Guides 4 min ### Why most people use MOTS-C wrong — and how to run it the way it’s designed to work Why most people use MOTS-C wrong — and how to run it the way it’s designed to work Quick take Most people run MOTS-C for fat loss and energy by itself, then wonder why the results don’t match what they expected. Using MOTS-C alone is like putting racing fuel in a car with a cracked engine block. The fuel isn’t the problem — the system can’t use it properly. Read article [Why most people use MOTS-C wrong — and how to run it the way it’s designed to work](https://peptidesupermarket.co.uk/research/why-most-people-use-mots-c-wrong-and-how-to-run-it-the-way-its-designed-to-work) --- *Add `.md` to any page URL on peptidesupermarket.co.uk for its Markdown version. Index of the site: https://peptidesupermarket.co.uk/llms.txt - full text: https://peptidesupermarket.co.uk/llms-full.txt.*