---
title: "Semaglutide Peptide UK - Compare Prices from 66 Suppliers - PeptideSupermarket®"
description: "Compare Semaglutide prices from 66 UK suppliers, from £10.95. Find the cheapest deals, read reviews and save money."
url: "https://peptidesupermarket.co.uk/peptide/semaglutide"
site: "PeptideSupermarket®"
country: "United Kingdom"
---

[Home](https://peptidesupermarket.co.uk) › [Peptides](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) › Semaglutide Search

# Semaglutide Price Comparison

Live prices from 66 UK suppliers, from £10.95, compared side by side so you never overpay.

[GLP-1 & metabolic research](https://peptidesupermarket.co.uk/compare-peptide-prices-uk) Prices checked 15 minutes ago

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Best Price £10.95

Average £48.04

Highest £140.00

You Could Save 92%

48 results 10mg

Compare 48 prices for Semaglutide. Cheapest: £10.95. Average: £48.04.

| Compare | Supplier | Price | Price / mg | Stock | Delivery | Quality | Coupon | Visit |
| --- | --- | --- | --- | --- | --- | --- | --- | --- |
| | 95 Confidence [SPT Peptide](https://peptidesupermarket.co.uk/suppliers/spt-peptide) ★★★★★ 5.0 (23) Semaglutide | £30.00 | £3.00/mg | In Stock | Free over £100 | Lab Tested | — | Visit |
| | 95 Confidence [Owsa Labs](https://peptidesupermarket.co.uk/suppliers/owsa-labs) ★★★★★ 5.0 (15) Semaglutide | £29.99 | £3.00/mg | Out of Stock | Free | Lab Tested | — | Visit |
| | 92 Confidence [Pyrox Labs](https://peptidesupermarket.co.uk/suppliers/pyrox-labs) ★★★★★ 5.0 (1) Semaglutide | £31.00 | £3.10/mg | In Stock | Free over £50 | Lab Tested | — | Visit |
| | 90 Confidence [Cobalt Peptides](https://peptidesupermarket.co.uk/suppliers/cobalt-peptides) ★★★★★ 5.0 (19) Semaglutide | £31.95 | £3.20/mg | Out of Stock | Free over £75 | Lab Tested | — | Visit |
| | 88 Confidence [Cedar Peptides](https://peptidesupermarket.co.uk/suppliers/cedar-peptides) ★★★★★ 5.0 (1) Semaglutide 10mg | £43.95 | £4.40/mg | In Stock | Free over £100 | Lab Tested | — | Visit |
| | 88 Confidence [Adria](https://peptidesupermarket.co.uk/suppliers/adria) Semaglutide 10mg | £66.80 | £6.68/mg | In Stock | Free | — | — | Visit |
| | 87 Confidence [Astra Labs](https://peptidesupermarket.co.uk/suppliers/astra-labs) Semaglutide 10mg | £25.99 | £2.60/mg | Out of Stock | Free | Lab Tested | — | Unavailable |
| | 80 Confidence [Raccoon Peptides](https://peptidesupermarket.co.uk/suppliers/raccoon-peptides) ★★★★★ 5.0 (1) Semaglutide 10mg | £49.00 | £4.90/mg | In Stock | Free | Lab Tested | — | Unavailable |
| | 80 Confidence [JG Peptides Plus](https://peptidesupermarket.co.uk/suppliers/jg-peptides-plus) Semaglutide | £30.00 | £3.00/mg | In Stock | Free over £100 | Lab Tested | — | Visit |
| | 79 Confidence [Pepts](https://peptidesupermarket.co.uk/suppliers/pepts) Semaglutide | £49.99 | £5.00/mg | In Stock | Free over £80 | Lab Tested | — | Visit |
| | 77 Confidence [Lucid Peptides](https://peptidesupermarket.co.uk/suppliers/lucid-peptides) Semaglutide Pen | £29.75 | £2.98/mg | In Stock | Free | Lab Tested | — | Visit |
| | 75 Confidence [MKM Biolabs](https://peptidesupermarket.co.uk/suppliers/mkm-biolabs) ★★★★★ 5.0 (1) Semaglutide | £33.99 | £3.40/mg | In Stock | Free over £100 | Lab Tested | — | Visit |
| | 74 Confidence [ExtolX](https://peptidesupermarket.co.uk/suppliers/extolx) ★★★★★ 4.8 (6) Semaglutide | £44.99 | £4.50/mg | In Stock | Free | Lab Tested | — | Visit |
| | 73 Confidence [Polygon Peptides](https://peptidesupermarket.co.uk/suppliers/polygon-peptides) Semaglutide | £49.99 | £5.00/mg | In Stock | Free | Lab Tested | — | Visit |
| | 70 Confidence [Nova Biolabs](https://peptidesupermarket.co.uk/suppliers/nova-biolabs) ★★★★★ 5.0 (17) Semaglutide 10mg | £20.00 | £2.00/mg | In Stock | £9.99 | — | — | Visit |
| | 70 Confidence [Nova Biolabs](https://peptidesupermarket.co.uk/suppliers/nova-biolabs) ★★★★★ 5.0 (17) Semaglutide 10mg | £20.00 | £2.00/mg | In Stock | £9.99 | — | — | Visit |
| | 66 Confidence [Elevate Peptides](https://peptidesupermarket.co.uk/suppliers/elevate-peptides) Semaglutide 10mg | £45.99 | £4.60/mg | In Stock | Free | — | — | Visit |
| | 66 Confidence [Elevate Peptides](https://peptidesupermarket.co.uk/suppliers/elevate-peptides) Semaglutide | £45.99 | £4.60/mg | In Stock | Free | — | — | Visit |
| | 63 Confidence [Opti-Gen Peptides](https://peptidesupermarket.co.uk/suppliers/opti-gen-peptides) ★★★★★ 4.8 (8) Semaglutide | £28.00 | £2.80/mg | In Stock | Free | Lab Tested | — | Visit |
| | 62 Confidence [MyPep Biotech](https://peptidesupermarket.co.uk/suppliers/my-pepbiotech) Semaglutide | £29.99 | £3.00/mg | In Stock | Free | — | — | Visit |
| | 62 Confidence [MyPep Biotech](https://peptidesupermarket.co.uk/suppliers/my-pepbiotech) Semaglutide Pen | £49.99 | £5.00/mg | In Stock | Free | — | — | Visit |
| | 60 Confidence [Power Peptides](https://peptidesupermarket.co.uk/suppliers/power-peptides) Semaglutide 10mg | £30.00 | £3.00/mg | In Stock | Free | — | — | Visit |
| | 55 Confidence [RS Bio Labs](https://peptidesupermarket.co.uk/suppliers/rs-bio-labs) Semaglutide | £17.99 | £1.80/mg | In Stock | Free over £100 | Lab Tested | — | Visit |
| | 50 Confidence [BioVanta Research](https://peptidesupermarket.co.uk/suppliers/biovanta-research) ★★★★★ 4.5 (23) Semaglutide 10mg | £74.95 | £7.50/mg | In Stock | Free | Lab Tested | — | Visit |
| | 50 Confidence [Blue Peak Peptides](https://peptidesupermarket.co.uk/suppliers/blue-peak-peptides) ★★★★★ 5.0 (1) Semaglutide | £29.95 | £3.00/mg | In Stock | Free | Lab Tested | — | Visit |

Showing 25 of 48 listings

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## Semaglutide Profile

Fda Approved FDA Approved

GLP-1 Receptor Agonist | Weight Loss & Diabetes

### Overview

Long-acting GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management. Over 17,000 trial participants have demonstrated significant efficacy through appetite suppression and glycemic control. The 7-day half-life enables convenient weekly dosing.

### Mechanism of Action

Mimics native GLP-1, binding to receptors to stimulate glucose-dependent insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite via hypothalamic pathways.

### Key Benefits

- 15-20% average body weight reduction
- Established cardiovascular protection
- Convenient once-weekly dosing options
- Comprehensive safety data from extensive trials
- Flexible injectable and oral formulations

### Quick Stats

Typical Dose

0.25mg starting, titrate to 1-2.4mg weekly

Frequency

Once weekly (same day each week)

Cycle Duration

Ongoing therapy as prescribed

Storage

Pen: 2-8°C before first use, room temp up to 56 days after. Compounded: 2-8°C

## Molecular Information

Molecular Weight

4,113.64 Da

Length

31 amino acids

Type

GLP-1 receptor agonist

Half-Life

~7 days (168 hours)

### Amino Acid Sequence

One-letter: `HUEGTFTSDVSSYLEGQAAKEFIAWLVRGRG`

His

1

Histidine

Position 1

Aib

2

Aminoisobutyric Acid

Position 2

Glu

3

Glutamic Acid

Position 3

Gly

4

Glycine

Position 4

Thr

5

Threonine

Position 5

Phe

6

Phenylalanine

Position 6

Thr

7

Threonine

Position 7

Ser

8

Serine

Position 8

Asp

9

Aspartic Acid

Position 9

Val

10

Valine

Position 10

Ser

11

Serine

Position 11

Ser

12

Serine

Position 12

Tyr

13

Tyrosine

Position 13

Leu

14

Leucine

Position 14

Glu

15

Glutamic Acid

Position 15

Gly

16

Glycine

Position 16

Gln

17

Glutamine

Position 17

Ala

18

Alanine

Position 18

Ala

19

Alanine

Position 19

Lys

20

Lysine

Position 20

Glu

21

Glutamic Acid

Position 21

Phe

22

Phenylalanine

Position 22

Ile

23

Isoleucine

Position 23

Ala

24

Alanine

Position 24

Trp

25

Tryptophan

Position 25

Leu

26

Leucine

Position 26

Val

27

Valine

Position 27

Arg

28

Arginine

Position 28

Gly

29

Glycine

Position 29

Arg

30

Arginine

Position 30

Gly

31

Glycine

Position 31

N-terminus C-terminus

Hydrophobic

Polar

Positive (+)

Negative (-)

Modified

### Modifications

Acylated with C18 fatty diacid via γ-Glu spacer

## Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Weight Loss Diabetes Metabolic

## Dosing Protocols

### injectable

Pre-filled pen devices for once-weekly subcutaneous injection. Brands include Ozempic (diabetes) and Wegovy (weight loss).

| Goal | Dose | Frequency | Route |
| --- | --- | --- | --- |
| Weight Loss Initiation | 0.25mg | Weekly x 4 weeks, then increase | Subcutaneous |
| Weight Loss Maintenance | 2.4mg | Weekly (after 16-week titration) | Subcutaneous |
| Diabetes Management | 0.5-1mg | Weekly | Subcutaneous |
| Cardiovascular Protection | 0.5-1mg | Weekly | Subcutaneous |
| Tolerability-Based | 0.25-2.4mg | Weekly (individualized) | Subcutaneous |

#### Key Tips

- Once-weekly dosing
- Abdomen, thigh, or upper arm injection sites
- Pre-filled pens available

Reconstitution Instructions

### oral

Rybelsus tablets use SNAC technology for enhanced absorption. Requires strict administration protocol.

| Goal | Dose | Frequency | Route |
| --- | --- | --- | --- |
| Diabetes Initiation | 3mg | Daily x 30 days | Oral (empty stomach) |
| Standard Diabetes Dose | 7mg | Once daily | Oral (empty stomach) |
| Maximum Diabetes Dose | 14mg | Once daily | Oral (empty stomach) |

#### Key Tips

- No injection required
- Daily dosing maintains consistent levels
- SNAC technology enhances absorption

Reconstitution Instructions

## Peptide Interactions

#### Insulin

Monitor

May increase hypoglycemia risk when combined; requires blood glucose monitoring.

#### Tirzepatide

Avoid

Both are incretin mimetics with overlapping mechanisms; concurrent use increases side effects.

#### Cagrilintide

Synergistic

Combined as CagriSema in clinical trials for enhanced weight loss efficacy.

#### Metformin

Compatible

Commonly used together for diabetes management with good safety profile.

#### BPC-157

Compatible

No contraindications; may help with GI side effects.

#### Sulfonylureas

Monitor

Increased hypoglycemia risk; may require sulfonylurea dose reduction.

#### Oral Medications

Requires Timing

Delayed gastric emptying may affect absorption of oral medications.

## What to Expect

Week 1-4

Mild appetite reduction, possible nausea during initial dose

Month 2-3

Noticeable weight loss (5-10% typical), improved satiety

Month 4-6

Continued weight loss (10-15% common), stable glucose levels

Month 6+

Weight loss plateau possible, focus on maintenance

Diabetes

Blood sugar improvements within 1-2 weeks

## Side Effects & Safety

#### Common Side Effects

- Nausea
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain

#### Monitoring

- Blood glucose levels
- Signs of pancreatitis
- Thyroid nodules
- Kidney function

#### Stop Signs

- Severe persistent abdominal pain (possible pancreatitis)
- Persistent vomiting preventing fluid intake
- Signs of thyroid tumor (neck lump, hoarseness, trouble swallowing)
- Severe allergic reaction (rash, itching, difficulty breathing)
- Vision changes (possible diabetic retinopathy progression)
- Severe hypoglycemia (if combined with insulin/sulfonylureas)
- Kidney problems (decreased urination, swelling)

#### Contraindications

- Personal or family history of medullary thyroid cancer
- Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
- Pregnancy or breastfeeding
- History of pancreatitis

## Quality Checklist

#### Good Signs

- FDA-approved branded products (Ozempic, Wegovy, Rybelsus)
- Proper refrigeration verified and not expired
- Clear, colorless to slightly yellow solution in pen/vial

#### Warning Signs

- Compounded versions - FDA warns about untested compounded semaglutide

#### Bad Signs

- Cloudy or discolored solution
- Particles or precipitation visible
- Non-pharmacy sources or unverified online sellers

## Research & References

### Key References

1. 2021

#### STEP 1 Trial - Weight Management

14.9% average weight loss versus 2.4% with placebo over 68 weeks with 2.4mg weekly.
2. 2023

#### SELECT Cardiovascular Outcomes

20% reduction in major adverse cardiovascular events over 5 years with 2.4mg weekly.
3. 2016

#### SUSTAIN Diabetes Program

Average HbA1c reductions of 1.5-1.8% across multiple trials.
4. 2022

#### STEP 5 Two-Year Maintenance

Sustained weight loss of 15.2% at week 104 with 2.4mg weekly.
5. 2019

#### PIONEER Oral Semaglutide

Oral efficacy comparable to injectable formulations at 3-14mg daily.
6. 2022

#### STEP TEENS Adolescent Study

16.1% BMI reduction in adolescent population over 68 weeks.

[Search PubMed for Semaglutide](https://pubmed.ncbi.nlm.nih.gov/?term=%28%22Semaglutide%22%20OR%20%22Semaglutide%20%28Glucagon-Like%20Peptide-1%20Receptor%20Agonist%29%22%20OR%20%22Ozempic%22%20OR%20%22Wegovy%22%20OR%20%22Rybelsus%22%29)

Research Library

## Semaglutide research & guides

Plain-English guides and study summaries from published literature.

[View all 2](https://peptidesupermarket.co.uk/research/peptide/semaglutide)

![GLP-1s Aren’t Miracle Drugs—or Metabolism Killers](https://peptidesupermarket.co.uk/storage/130/conversions/01KH8JQ00F997B5598Z1X1BP8N-thumbnail.jpg) Guides 7 min

### GLP-1s Aren’t Miracle Drugs—or Metabolism Killers

Most guys hear “GLP-1” and immediately land in one of two camps: Camp 1: “It’s a miracle drug that melts fat with zero downside.” Camp 2: “It’ll destroy your body—lose muscle, wreck your metabolism, end up frail.”

Read article

[GLP-1s Aren’t Miracle Drugs—or Metabolism Killers](https://peptidesupermarket.co.uk/research/glp-1s-arent-miracle-drugs-or-metabolism-killers)

![Semaglutide: is it the right tool for you, or is there a better option now?](https://peptidesupermarket.co.uk/storage/123/conversions/01KH8JP66RPK705G57TVEV00BK-thumbnail.jpg) Guides 6 min

### Semaglutide: is it the right tool for you, or is there a better option now?

Semaglutide works because it makes a calorie deficit easier to sustain. It suppresses appetite, slows gastric emptying, and helps you feel full longer. But it doesn’t burn fat directly, it can come with a real lean-mass loss problem, and a lot of people regain weight after stopping unless they use that appetite-suppression window to build habits. And if your real goal is fat loss and body composition, there are newer options that generally perform better.

Read article

[Semaglutide: is it the right tool for you, or is there a better option now?](https://peptidesupermarket.co.uk/research/semaglutide-is-it-the-right-tool-for-you-or-is-there-a-better-option-now)

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