Crystagen Price Comparison

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Best Price £39.95
Average £46.65
Highest £54.99
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Crystagen Profile

Moderate Research

EDP Tripeptide | Thymus Immune Bioregulator

Overview

Crystagen is a Khavinson bioregulator tripeptide (EDP) identified in thymalin with selective action on thymus tissues. Developed at Russia's St. Petersburg Institute of Bioregulation and Gerontology, it enhances immune function by stimulating normal lymphocyte proliferation while inhibiting tumor cell growth. Research shows effectiveness in normalizing immunity in 82% of elderly patients (vs 56% control) and reducing respiratory infections in athletes by doubling HSP gene expression.

Mechanism of Action

Crystagen works through epigenetic regulation by influencing gene expression and protein synthesis in immune cells. It regulates the synthesis of heat-shock proteins, cytokines, and affects cell differentiation, proliferation, and apoptosis. The EDP peptide enhances spontaneous proliferative activity of normal lymphocytes while inhibiting proliferation of tumor cells (K-562 erythromyelosis). It activates B-cell immune system and thymic epithelial cells (VTEC2.H/S).

Key Benefits

  • Normalizes immune function in 82% of patients
  • Stimulates normal lymphocyte proliferation
  • Inhibits tumor cell growth (antitumor activity)
  • Doubles HSP gene expression (stress resistance)
  • Reduces respiratory viral infections
  • Activates B-cell immune system
  • Normalizes IL-6 expression
  • Effective after radiation/chemotherapy

Quick Stats

Typical Dose
10-20 mg daily
Frequency
Once daily for 10-20 consecutive days
Cycle Duration
10-20 days per cycle
Storage
Capsules: room temperature; Injectable lyophilized: 2-8°C; Reconstituted: 2-8°C refrigerated

Molecular Information

Molecular Weight
359 Da
Length
3 amino acids
Type
Tripeptide bioregulator
Half-Life
Minutes (short peptide); effects persist via epigenetic changes

Amino Acid Sequence

One-letter: EDP
Glu
1

Glutamic Acid

Position 1

Asp
2

Aspartic Acid

Position 2

Pro
3

Proline

Position 3

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Immune Dysfunction

Effective

Normalizes immunogram in elderly patients with impaired immunity.

Post-Infection Recovery

Effective

Restores immune function after infectious diseases.

Radiation/Chemo Recovery

Effective

Helps normalize immunity after radiation and chemotherapy exposure.

Athletic Immune Support

Effective

Increases stress resistance and reduces respiratory infections in athletes.

HSP Expression

Effective

Doubles expression of heat-shock protein gene HSPA1A.

Tumor Cell Inhibition

Moderate

Inhibits proliferation of K-562 human erythromyelosis tumor cells.

Dosing Protocols

oral

Available in capsule form for oral administration. Short peptides can be absorbed orally and reach target tissues. Typical protocol involves 10-20 day cycles, often repeated 2-3 times per year.

Goal Dose Frequency Route
Standard protocol 10-20 mg Daily for 10-20 days Oral capsules
Maintenance 10 mg 2-3 cycles yearly Oral capsules
Athletic support 10-20 mg Daily during training cycles Oral capsules

Key Tips

  • Convenient oral administration
  • Short peptide allows GI absorption
  • Room temperature storage for capsules

injectable

Injectable form available for direct administration.

Goal Dose Frequency Route
Research protocol 10 mg Daily for 10 days IM or SubQ

Key Tips

  • Direct absorption
  • Precise dosing
Materials Needed
Bacteriostatic water Insulin syringes Alcohol swabs Sterile vial
Steps
  1. 1 Clean work area thoroughly
  2. 2 Reconstitute with appropriate volume
  3. 3 Gently swirl until dissolved
  4. 4 Store reconstituted solution refrigerated

Peptide Interactions

Vilon

Synergistic

Both have immunoprotecting properties; different mechanisms complement each other.

Thymalin

Synergistic

Crystagen (EDP) is derived from thymalin; complementary immune effects.

Epitalon

Synergistic

Often combined in comprehensive anti-aging Khavinson protocols.

Thymogen

Compatible

Related immune peptides; can be used together.

What to Expect

During cycle

Immune activation and gene expression modulation begins

Post-cycle

Effects persist due to epigenetic changes

Weeks

Measurable immune function improvements

Long-term

Cumulative benefits with periodic cycles

Side Effects & Safety

Common Side Effects

  • Generally well-tolerated
  • Minimal side effects reported

Stop Signs

  • Allergic reactions
  • Unusual immune symptoms

Contraindications

  • Active autoimmune flares (consult physician)
  • Known hypersensitivity
  • Pregnancy or breastfeeding

Quality Checklist

Good Signs

  • White powder or capsules
  • Clear solution if reconstituted
  • Proper packaging and labeling

Warning Signs

  • Unknown source or purity

Bad Signs

  • Discoloration
  • Unusual odor
  • Damaged packaging

Research & References

Key References

  1. 2021

    The Use of Thymalin for Immunocorrection and Molecular Aspects of Biological Activity

    PMC/NCBI

    EDP (crystagen) identified in thymalin; regulates gene expression, HSP synthesis, cytokines, and cell differentiation.

  2. 2018

    Crystagen in Elderly Patients with Impaired Immunity

    Advances in Gerontology

    Crystagen normalized immunogram in 82% of patients vs 56% in control group.

  3. 2019

    Peptide Bioregulators in Athletes

    Bulletin of Experimental Biology and Medicine

    Crystagen doubled HSP gene expression, normalized IL-6, and reduced respiratory infections in athletes.

  4. 2017

    EDP Peptide Effects on Lymphocyte Proliferation

    Cell Technologies in Biology and Medicine

    EDP enhances normal lymphocyte proliferation while inhibiting K-562 tumor cell proliferation.

Search PubMed for Crystagen

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