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Growth hormone stimulation

GHRP 2 Price Comparison

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Stimulates natural growth hormone release Promotes muscle growth and recovery Enhances fat metabolism and weight loss Improves sleep quality Supports immune function and tissue repair

Based on published research findings only. Not medical claims. For laboratory research use only.

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40 suppliers · 7 dosages · 54 products
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£22.25
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GHRP 2 10mg

£23.99
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GHRP 2 10mg

£29.95
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GHRP 2 5mg

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GHRP 2 10mg

£29.99
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GHRP 2 10mg

£31.20
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GHRP 2 10mg

£32.00
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£33.16
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GHRP 2 5mg

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GHRP 2 20mg

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GHRP 2 10mg

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£47.00
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GHRP-2 5mg

£49.99
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GHRP 2 10mg

£52.99
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GHRP 2 100mg

£75.00
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GHRP 2 15mg

£78.99
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GHRP 2 Profile

Well Studied

Growth Hormone Releasing Peptide-2 | Pralmorelin

Overview

GHRP-2 is a synthetic growth hormone secretagogue that stimulates the pituitary gland to release growth hormone. It is one of the most potent members of the GHRP family, being 2-3 times more effective than GHRP-6 in stimulating GH release. Originally developed as a diagnostic agent for growth hormone deficiency, it works by mimicking ghrelin and binding to the GHS-R1a receptor.

Mechanism of Action

GHRP-2 acts as a synthetic agonist of ghrelin, binding to the growth hormone secretagogue receptor (GHS-R1a) in the hypothalamus and pituitary. This stimulates cAMP production and promotes pulsatile release of endogenous growth hormone without suppressing natural feedback loops. It works synergistically with GHRH to amplify GH secretion beyond what either peptide achieves alone.

Key Benefits

  • Potent stimulation of natural growth hormone release
  • Enhanced muscle growth and recovery
  • Improved body composition and fat metabolism
  • Better sleep quality and recovery
  • Increased appetite (can be beneficial for bulking)
  • Maintains natural GH pulsatile release patterns
  • Synergistic effects when combined with GHRH peptides

Quick Stats

Typical Dose
100-300 mcg
Frequency
2-3x daily
Cycle Duration
8-12 weeks
Storage
2-8°C refrigerated

Molecular Information

Molecular Weight
817.9 Da
Length
6 amino acids
Type
Synthetic hexapeptide
Half-Life
~30 minutes

Amino Acid Sequence

One-letter: ?A??AW?FK?
D
1

D

Position 1

Ala
2

Alanine

Position 2

D
3

D

Position 3

2Na
4

2Nal

Position 4

Ala
5

Alanine

Position 5

Trp
6

Tryptophan

Position 6

D
7

D

Position 7

Phe
8

Phenylalanine

Position 8

Lys
9

Lysine

Position 9

NH2
10

NH2

Position 10

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

GH Deficiency Assessment

Most Effective

Used as a diagnostic agent in Japan for assessing growth hormone deficiency in clinical settings.

Natural GH Stimulation

Most Effective

Stimulates endogenous growth hormone release through ghrelin receptor activation.

IGF-1 Elevation

Effective

Indirectly increases IGF-1 levels through enhanced GH secretion.

Muscle Growth

Effective

Enhanced muscle protein synthesis through elevated growth hormone and IGF-1 levels.

Fat Metabolism

Effective

Improved lipolysis and body composition through GH-mediated fat oxidation.

Recovery Enhancement

Effective

Faster recovery from exercise and improved sleep quality.

Muscle Protection

Moderate

Myoprotective effects in muscle atrophy models through GHS-R1a stimulation.

Cardioprotection

Moderate

Cytoprotective effects observed in cardiac tissue research.

Dosing Protocols

injectable

Subcutaneous injection is the primary administration route. Best administered on an empty stomach for optimal GH release. Multiple daily doses recommended to maintain elevated GH levels.

Goal Dose Frequency Route
GH optimization 100-150 mcg 2-3x daily SubQ
Enhanced results 200-300 mcg 2-3x daily SubQ
With GHRH (synergy) 100 mcg each 2-3x daily SubQ (combined)
Pre-sleep protocol 100-200 mcg Before bed SubQ

Key Tips

  • Administer on empty stomach (2+ hours after eating)
  • Wait 20-30 minutes before eating after injection
  • Best timing: morning, post-workout, and before bed
  • Avoid fats and carbs around administration for best GH release
Materials Needed
Bacteriostatic water (BAC) Insulin syringes (0.5-1 mL) Alcohol swabs Peptide vial Sterile work surface
Steps
  1. 1 Clean work area and hands thoroughly
  2. 2 Calculate required BAC water volume
  3. 3 Draw BAC water into syringe
  4. 4 Inject slowly down vial side (not directly onto powder)
  5. 5 Gently swirl until dissolved (never shake)
  6. 6 Store in refrigerator, use within 28 days

Peptide Interactions

CJC-1295

Synergistic

Powerful synergy; GHRH + GHRP combination amplifies GH release significantly.

Mod GRF 1-29

Synergistic

Classic GHRP + GHRH stack for enhanced growth hormone release.

Ipamorelin

Compatible

Both are GHRPs; can be alternated but typically not stacked together.

GHRP-6

Compatible

Similar mechanism; GHRP-2 is more potent with less appetite stimulation.

BPC-157

Compatible

No known negative interactions; different mechanisms.

What to Expect

Immediately

GH spike within 15-30 minutes of injection

Week 1-2

Improved sleep quality and recovery

Week 2-4

Noticeable improvements in energy and well-being

Week 4-8

Visible changes in body composition and muscle fullness

Week 8-12

Full benefits realized with consistent use

Side Effects & Safety

Common Side Effects

  • Increased appetite (less than GHRP-6)
  • Mild water retention
  • Tingling or numbness in extremities
  • Tiredness or lethargy after injection
  • Mild headache

Stop Signs

  • Severe or persistent headaches
  • Unusual swelling in hands or feet
  • Signs of carpal tunnel syndrome
  • Allergic reactions

Contraindications

  • Active cancer or history of cancer
  • Pregnancy or breastfeeding
  • Pituitary disorders
  • Diabetic retinopathy
  • WADA prohibited for competitive athletes

Quality Checklist

Good Signs

  • White to off-white lyophilized powder
  • Clear solution after reconstitution
  • Intact vacuum seal on vial

Warning Signs

  • Slight clumping that dissolves easily

Bad Signs

  • Discolored or yellow powder
  • Cloudy solution after reconstitution
  • Particles or precipitates in solution

Research & References

Key References

2010

Growth Hormone Releasing Peptide-2 increases food intake in healthy men

GHRP-2 infusion increased food intake by 35.9% compared to saline, demonstrating ghrelin-like orexigenic effects.

2017

Synthetic Growth Hormone-Releasing Peptides: Cytoprotective Effects

GHRPs including GHRP-2 demonstrated significant cytoprotective effects in cardiac and extracardiac tissues.

2000

GHRP-2 effects on growth hormone release in swine

Chronic GHRP-2 administration increased average daily gain by 22.35% and feed efficiency by 20.64%.

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