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Compare 3 prices for GHRP 2. Cheapest: £9.99. Average: £13.65.
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| £11.95 | £5.98/mg | Out of Stock | Free |
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| £9.99 | £5.00/mg | In Stock | £9.99 |
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| £19.00 | £9.50/mg | In Stock | Free |
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Growth Hormone Releasing Peptide-2 | Pralmorelin
GHRP-2 is a synthetic growth hormone secretagogue that stimulates the pituitary gland to release growth hormone. It is one of the most potent members of the GHRP family, being 2-3 times more effective than GHRP-6 in stimulating GH release. Originally developed as a diagnostic agent for growth hormone deficiency, it works by mimicking ghrelin and binding to the GHS-R1a receptor.
GHRP-2 acts as a synthetic agonist of ghrelin, binding to the growth hormone secretagogue receptor (GHS-R1a) in the hypothalamus and pituitary. This stimulates cAMP production and promotes pulsatile release of endogenous growth hormone without suppressing natural feedback loops. It works synergistically with GHRH to amplify GH secretion beyond what either peptide achieves alone.
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Position 1
Alanine
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D
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2Nal
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Alanine
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Tryptophan
Position 6
D
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Phenylalanine
Position 8
Lysine
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NH2
Position 10
Used as a diagnostic agent in Japan for assessing growth hormone deficiency in clinical settings.
Stimulates endogenous growth hormone release through ghrelin receptor activation.
Indirectly increases IGF-1 levels through enhanced GH secretion.
Enhanced muscle protein synthesis through elevated growth hormone and IGF-1 levels.
Improved lipolysis and body composition through GH-mediated fat oxidation.
Faster recovery from exercise and improved sleep quality.
Myoprotective effects in muscle atrophy models through GHS-R1a stimulation.
Cytoprotective effects observed in cardiac tissue research.
Subcutaneous injection is the primary administration route. Best administered on an empty stomach for optimal GH release. Multiple daily doses recommended to maintain elevated GH levels.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| GH optimization | 100-150 mcg | 2-3x daily | SubQ |
| Enhanced results | 200-300 mcg | 2-3x daily | SubQ |
| With GHRH (synergy) | 100 mcg each | 2-3x daily | SubQ (combined) |
| Pre-sleep protocol | 100-200 mcg | Before bed | SubQ |
Powerful synergy; GHRH + GHRP combination amplifies GH release significantly.
Classic GHRP + GHRH stack for enhanced growth hormone release.
Both are GHRPs; can be alternated but typically not stacked together.
Similar mechanism; GHRP-2 is more potent with less appetite stimulation.
No known negative interactions; different mechanisms.
GH spike within 15-30 minutes of injection
Improved sleep quality and recovery
Noticeable improvements in energy and well-being
Visible changes in body composition and muscle fullness
Full benefits realized with consistent use
Cellular and molecular life sciences : CMLS · Bowers CY
This review summarizes the development and endocrine pharmacology of synthetic growth hormone-releasing peptides, including GHRP-2, and discusses their actions on pituitary and hypothalamic growth hormone pathways.
The Journal of clinical endocrinology and metabolism · Laferrère B, Abraham C, Russell CD, Bowers CY
This controlled human study examined acute GHRP-2 administration in healthy men and reported increased short-term food intake alongside growth hormone secretory responses.
Nature · Kojima M, Hosoda H, Date Y, Nakazato M, Matsuo H, Kangawa K
This study identified ghrelin as an endogenous ligand for the growth hormone secretagogue receptor, linking the receptor pathway used by GHRP-class peptides to a stomach-derived hormone.
Trends in endocrinology and metabolism: TEM · Casanueva FF, Dieguez C
This review discusses the physiology and clinical investigation of growth hormone secretagogues, including growth hormone-releasing peptides such as GHRP-2 and their relationship to growth hormone release.
Plain-English guides and study summaries from published literature.
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