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Oxytocin 5mg
Oxytocin 5mg
Oxytocin
Oxytocin 5mg
Oxytocin 5mg
Oxytocin 5mg
Oxytocin 5mg
Compare 13 prices for Oxytocin. Cheapest: £19.95. Average: £35.09.
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| £19.99 | £4.00/mg | In Stock | Free over £75 |
Lab Tested
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| £19.95 | £3.99/mg | Out of Stock | Free |
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| £20.00 | £4.00/mg | In Stock | Free |
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| £20.00 | £4.00/mg | In Stock | Free |
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| £100.80 | £20.16/mg | In Stock | Free over £100 |
Lab Tested
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| £20.00 | £4.00/mg | In Stock | Free |
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| £24.00 | £4.80/mg | Low Stock | Free over £200 |
Lab Tested
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| £25.00 | £5.00/mg | In Stock | Free |
Lab Tested
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| £25.00 | £5.00/mg | In Stock | Free |
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| £35.00 | £7.00/mg | In Stock | Free |
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| £35.00 | £7.00/mg | In Stock | £9.99 |
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| £48.99 | £9.80/mg | In Stock | Free |
Lab Tested
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| £62.50 | £12.50/mg | In Stock | Free |
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Neurohypophysial Peptide | Social Bonding & Reproductive Hormone
Nine-amino-acid peptide hormone produced in hypothalamus, released by posterior pituitary. Functions in social bonding, trust, empathy, reproduction, childbirth, lactation. FDA-approved synthetically for labor induction and postpartum hemorrhage.
Binds oxytocin receptors on uterine smooth muscle, triggering calcium influx and myometrial contractions. Stimulates prostaglandin release. In CNS, modulates GABAergic, serotonergic, dopaminergic neurotransmission; reduces cortisol and HPA axis activity.
CYIQNCPLG?
Cysteine
Position 1
Tyrosine
Position 2
Isoleucine
Position 3
Glutamine
Position 4
Asparagine
Position 5
Cysteine
Position 6
Proline
Position 7
Leucine
Position 8
Glycine
Position 9
NH2
Position 10
Initiates or augments uterine contractions when vaginal delivery medically indicated.
Controls postpartum bleeding through uterine contraction stimulation during third stage.
Adjunctive therapy for incomplete or inevitable abortion in second trimester.
Extensive research with mixed results on social functioning; optimal dosing unclear.
Combined with exposure therapy; shows reduced PTSD/depression symptoms.
Decreases amygdala reactivity to social threats; normalizes brain connectivity.
Improves libido, arousal, orgasm intensity in both sexes.
IV or IM administration in clinical settings. IV provides immediate onset; requires continuous infusion and monitoring for labor use.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Labor Induction | 0.5-2 mU/min initial, titrate to 1-2 mU/min every 30-60 min | Continuous IV infusion | IV (diluted) |
| Postpartum Hemorrhage Prevention | 10 units IM or 10-40 units in IV solution | Single dose after placental delivery | IM or IV infusion |
Nasal spray delivers oxytocin directly to brain via olfactory and trigeminal pathways, bypassing blood-brain barrier. Primary research route for psychological/social effects.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Social anxiety/bonding enhancement | 20-24 IU | Once daily or before social situations | Intranasal spray |
| Autism research protocols | 24-48 IU daily | Twice daily | Intranasal spray |
| PTSD therapy augmentation | 40 IU | Before therapy sessions | Intranasal spray |
| Sexual function enhancement | 24-40 IU | 30-45 minutes before activity | Intranasal spray |
Sublingual troches provide needle-free administration. Lower bioavailability (~4.5% vs 11% intranasal) requires higher doses.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| General wellness/bonding support | 50-100 IU | Once daily | Sublingual troche |
| Sexual function support | 100 IU | 30-45 minutes before activity | Sublingual troche |
Structurally similar; overlapping receptor affinity with potential additive effects.
Complementary anxiolytic effects—Selank modulates GABA; oxytocin acts on central receptors.
Complementary sexual function effects via different pathways.
Both involved in reproduction; kisspeptin stimulates GnRH; oxytocin enhances arousal.
No direct interactions; different mechanisms (tissue repair vs social function).
SSRIs may affect endogenous oxytocin; combined use requires healthcare provider oversight.
Alcohol suppresses oxytocin release; reduces therapeutic effects.
IV: 1-3 minute onset, 30-60 minute duration; IM: 3-5 minute onset
15-30 minute onset, peak 30-60 minutes, 2-4 hour duration
30-45 minute onset, peak ~60 minutes, 2-4 hour duration
Proceedings of the National Academy of Sciences of the United States of America · Nishimori K, Young LJ, Guo Q, Wang Z, Insel TR, Matzuk MM
This mouse knockout study found that oxytocin-deficient females could mate and give birth but showed impaired milk ejection and nursing-related physiology.
Nature genetics · Ferguson JN, Young LJ, Hearn EF, Matzuk MM, Insel TR, Winslow JT
This study reported that mice lacking the oxytocin gene had impaired social recognition while several nonsocial memory measures were comparatively preserved.
Physiological reviews · Gimpl G, Fahrenholz F
This review summarized oxytocin receptor structure, signaling pathways, tissue distribution, regulation, and physiological roles in reproductive and central nervous system contexts.
Nature · Kosfeld M, Heinrichs M, Zak PJ, Fischbacher U, Fehr E
This double-blind experiment found that intranasal oxytocin was associated with larger monetary transfers in a trust game, without a comparable change in a nonsocial risk task.
The Journal of neuroscience : the official journal of the Society for Neuroscience · Kirsch P, Esslinger C, Chen Q, Mier D, Lis S, Siddhanti S, Gruppe H, Mattay VS, Gallhofer B, Meyer-Lindenberg A
This functional neuroimaging study reported altered amygdala activation and connectivity during social and fear-related tasks after intranasal oxytocin administration.
The New England journal of medicine · Sikich L, Kolevzon A, King BH, McDougle CJ, Sanders KB, Kim SJ, Spanos M, Chandrasekhar T, Trelles MDP, Rockhill CM, Palumbo ML, Witters Cundiff A, Montgomery A, Siper P, Minjarez M, Nowinski LA, Marler S, Shuffrey LC, Alderman C, Weissman J, Zappone B, Mullett JE, Crosson H, Hong N, Siecinski SK, Giamberardino SN, Luo S, She L, Bhapkar M, Dean R, Scheer A, Johnson JL, Gregory SG, Veenstra-VanderWeele J
This randomized clinical trial in children and adolescents with autism spectrum disorder found no significant between-group difference versus placebo on the primary social-functioning endpoint over 24 weeks.
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