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PT-141 10mg
PT-141
PT-141
PT-141 10mg
PT-141
PT-141 10mg
PT-141
PT-141 10mg
PT-141
PT-141 10mg
PT-141
PT-141 10mg
PT-141
PT-141 10mg
PT-141 10mg
PT-141
PT-141
Compare 154 prices for PT-141. Cheapest: £5.00. Average: £28.62.
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| £20.00 | £2.00/mg | In Stock | Free over £100 |
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| £17.99 | £1.80/mg | Out of Stock | Free |
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| £24.00 | £2.40/mg | In Stock | Free over £100 |
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| £29.99 | £3.00/mg | In Stock | Free |
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| £18.99 | £1.90/mg | In Stock | Free over £100 |
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| £19.99 | £2.00/mg | In Stock | Free |
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| £29.00 | £2.90/mg | In Stock | Free over £100 |
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| £29.99 | £3.00/mg | In Stock | Free |
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| £17.00 | £1.70/mg | In Stock | Free over £50 |
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| £16.00 | £1.60/mg | In Stock | Free |
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| £20.00 | £2.00/mg | In Stock | Free |
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| £21.95 | £2.20/mg | In Stock | Free over £75 |
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| £16.99 | £1.70/mg | In Stock | Free over £150 |
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| £30.00 | £3.00/mg | In Stock | Free |
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| £33.40 | £3.34/mg | In Stock | Free |
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| £19.99 | £2.00/mg | In Stock | Free over £75 |
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| £16.00 | £1.60/mg | In Stock | Free |
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| £16.90 | £1.69/mg | In Stock | Free |
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| £25.00 | £2.50/mg | In Stock | Free over £100 |
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| £16.99 | £1.70/mg | In Stock | Free |
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| £17.99 | £1.80/mg | In Stock | Free over £80 |
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| £23.95 | £2.40/mg | In Stock | Free |
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| £18.99 | £1.90/mg | Out of Stock | £9.99 |
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| £19.99 | £2.00/mg | In Stock | Free over £100 |
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| £14.99 | £1.50/mg | In Stock | Free |
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Melanocortin Receptor Agonist | Sexual Dysfunction Treatment
FDA-approved melanocortin receptor agonist for treatment of hypoactive sexual desire disorder (HSDD) in premenopausal women. Works centrally in the nervous system to trigger sexual arousal pathways independent of vascular mechanisms, unlike traditional ED medications.
Selectively activates melanocortin receptors (MC3R/MC4R) in the central nervous system, triggering sexual arousal pathways independent of peripheral vascular mechanisms. Works within 45 minutes with effects lasting 6-12 hours.
FDA-approved for treatment of HSDD in premenopausal women.
Effective in men including PDE5 inhibitor-resistant cases via CNS pathways.
Enhances sexual arousal and desire in women.
Reduces distress related to low sexual desire.
Enhanced satisfaction reported in clinical trials.
Subcutaneous injection is the FDA-approved route. Administered 45-60 minutes before anticipated sexual activity.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Female HSDD (FDA-approved) | 1.75mg | As needed, max 1 dose/24hr | SubQ |
| Male Erectile Dysfunction | 1-2mg | As needed, 45-60min before activity | SubQ |
| Female Arousal Disorder | 0.75-1.25mg | As needed, max 1 dose/24hr | SubQ |
| Low Starting Dose | 0.5mg | Test dose for tolerance assessment | SubQ |
Intranasal spray with faster onset (30-45 minutes). Limited clinical data compared to injectable.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Male ED - Standard | 1.5-2mg | As needed, 30-45min before | Nasal |
| Female Sexual Dysfunction | 1-1.5mg | As needed, max 1 dose/24hr | Nasal |
PT-141 works centrally; PDE5 inhibitors work peripherally - monitor for additive BP effects.
Both are melanocortin agonists; combining risks excessive activation and side effects.
PT-141 can transiently lower blood pressure - monitor closely.
Both lower BP and cause flushing - limit intake to avoid excessive hypotension.
Risk of severe hypotension - contraindicated with heart condition medications.
Different mechanisms; no known interactions.
May work synergistically for sexual dysfunction through different pathways.
Different pathways (melanocortin vs GnRH) - no receptor overlap but monitor BP effects.
Mild nausea or facial flushing possible
Onset of effects - increased arousal and desire
Peak effects - enhanced sexual response
Gradual diminishment of effects
Journal of Sexual Medicine
Real-world data of 10,000+ prescriptions shows consistent safety profile.
International Journal of Impotence Research
Demonstrates effectiveness in patients who failed traditional ED medications.
Phase 3 trials with 1.75mg subcutaneous in premenopausal women showed 24.5% improvement vs 17.2% placebo, achieving statistical significance.
1-20mg intranasal showed dose-dependent erectile response, effective including in PDE5 inhibitor-resistant cases via CNS pathways.
In vitro and animal studies confirmed selective MC3R/MC4R binding activating sexual arousal without peripheral vasodilation.
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