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Semax
Semax 5mg
Semax
Semax 5mg
Semax
Semax 5mg
Semax
Semax 5mg
Semax 5mg
Semax 5mg
Semax 5mg
Semax 5mg
Semax 5mg
Compare 63 prices for Semax. Cheapest: £12.00. Average: £22.57.
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| £17.99 | £3.60/mg | In Stock | Free |
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| £19.99 | £4.00/mg | In Stock | Free |
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| £19.99 | £4.00/mg | In Stock | Free |
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| £18.95 | £3.79/mg | Out of Stock | Free over £75 |
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| £27.80 €32.49 EUR | £5.56/mg | In Stock | Free |
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| £20.95 | £4.19/mg | Out of Stock | Free over £100 |
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| £14.99 | £3.00/mg | In Stock | Free over £75 |
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| £19.99 | £4.00/mg | In Stock | £5.15 |
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| £17.99 | £3.60/mg | In Stock | Free |
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| £15.22 | £3.04/mg | In Stock | Free over £80 |
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| £18.95 | £3.79/mg | Out of Stock | Free |
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| £18.99 | £3.80/mg | In Stock | Free over £60 |
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| £15.99 | £3.20/mg | In Stock | Free over £50 |
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| £24.99 | £5.00/mg | In Stock | Free |
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| £12.00 | £2.40/mg | In Stock | Free |
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| £16.99 | £3.40/mg | In Stock | Free |
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| £13.99 | £2.80/mg | In Stock | Free over £50 |
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| £15.00 | £3.00/mg | In Stock | Free |
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| £15.00 | £3.00/mg | In Stock | £9.99 |
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| £15.95 | £3.19/mg | In Stock | Free |
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| £16.95 | £3.39/mg | In Stock | Free |
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| £16.99 | £3.40/mg | Out of Stock | Free |
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| £16.99 | £3.40/mg | Out of Stock | Free |
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| £17.55 | £3.51/mg | In Stock | £9.99 |
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| £17.99 | £3.60/mg | Out of Stock | Free |
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Synthetic ACTH Analog | Nootropic & Neuroprotective Peptide
Semax is a synthetic heptapeptide derived from adrenocorticotropic hormone (ACTH) fragment 4-10, originally developed in Russia for stroke recovery. It achieves enhanced CNS penetration through direct transport via olfactory epithelium and trigeminal nerves, bypassing the blood-brain barrier.
Rapidly increases BDNF levels, modulates dopaminergic and serotonergic systems, and achieves direct brain delivery through olfactory transport with 0.093% blood-brain barrier penetration (vs 0.01% IV).
MEHFPGP
Methionine
Position 1
Glutamic Acid
Position 2
Histidine
Position 3
Phenylalanine
Position 4
Proline
Position 5
Glycine
Position 6
Proline
Position 7
Improved short-term and working memory performance in fatigued individuals (71% vs 41% accuracy).
Enhanced sustained attention during demanding cognitive tasks.
Faster acquisition of new information and improved retention.
Accelerated rehabilitation with increased BDNF levels in stroke patients.
Supports recovery from traumatic brain injury.
Shows anti-amyloid properties in Alzheimer's models.
Supports neurogenesis through increased brain-derived neurotrophic factor.
Enhanced neural connections and brain network activity.
Improved ability to cope with cognitive stress.
Intranasal is the primary and most effective route, providing direct brain delivery through olfactory transport. Onset 15-30 minutes, peak 1-2 hours, duration 4-6 hours.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Cognitive enhancement | 300-600mcg | 1-2x daily | Intranasal spray/drops |
| Intensive cognitive support | 600-900mcg | 2-3x daily | Intranasal |
| Brain injury recovery | 900-1500mcg | 2-3x daily | Intranasal |
Subcutaneous injection provides reliable dosing. Onset 30-60 minutes, peak 2-4 hours, duration 6-8 hours.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Research protocol | 500-750mcg | 1x daily | SubQ |
| Intensive protocol | 750-1000mcg | 1-2x daily | SubQ |
Do NOT use simultaneously. Choose one or the other - they are variants of the same peptide.
Complementary anxiolytic effects; popular combination.
Both support neuroplasticity through different mechanisms.
Comprehensive neuroprotection when combined.
May enhance stimulant effects - monitor carefully and reduce stimulant doses.
Theoretical monoamine system risk; use caution.
Initial cognitive clarity and focus enhancement, possible mild nasal sensation
Improved attention span during demanding tasks
Enhanced memory consolidation, stable mood
Peak cognitive benefits with improved stress resilience and mental flexibility
Gradual baseline return over 3-7 days; some benefits persist
ACS Chemical Neuroscience
Demonstrated anti-amyloid properties with potential Alzheimer's applications.
Neuroscience Research Reviews
Updated review of BDNF enhancement mechanisms.
Clinical Pharmacology Research
Intranasal administration achieves 0.093% blood-brain barrier penetration versus 0.01% with intravenous.
Human study with 250-1000mcg intranasal single dose showed 71% accuracy on memory tests vs 41% in controls.
110 patients with ischemic stroke showed increased BDNF levels correlated with early rehabilitation when using Semax with conventional therapy.
24 healthy middle-aged participants showed increased fMRI default mode network activity relative to placebo.
Rat focal ischemia model showed Semax affected expression of 96 genes related to immune and vascular systems.
Plain-English guides and study summaries from published literature.
Guides
5 min
Semax is a short synthetic peptide (7 amino acids) originally developed for stroke and brain injury recovery. It’s used in Russia as a prescription medication, and it’s been positioned as a way to enhance brain plasticity and resilience without the “wired” feel you’d expect from stimulants. The core idea is simple: Increase BDNF (the brain’s growth-and-repair signal) Support neurotransmitter efficiency (especially dopamine responsiveness and serotonin turnover)
Read article
Guides
4 min
What Semax is Semax is a synthetic heptapeptide—seven amino acids in a very specific sequence. It’s built from a fragment of ACTH (adrenocorticotropic hormone), but not as a simple copy. The point is taking a biologically meaningful signal and making it more targeted and more potent for brain performance and protection.
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