Vilon Price Comparison

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£35.00
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£50.00
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£49.99
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Vilon 20mg

£70.00
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Vilon Profile

Moderate Research

KE Dipeptide | Thymus Immune Bioregulator

Overview

Vilon is a Khavinson bioregulator dipeptide (KE) consisting of lysine and glutamic acid, originally isolated from thymus gland extracts. Developed by Professor Vladimir Khavinson at the St. Petersburg Institute of Bioregulation and Gerontology, it acts as a molecular signaling compound that restores normal gene expression and protein synthesis in immune and epithelial cells. Research shows Vilon increases mean lifespan by 20-40% in animal studies and suppresses tumor development.

Mechanism of Action

Vilon works through epigenetic modulation, restoring chromatin structure and gene expression in immune cells. It stimulates thymocyte proliferation, activates T-helper cells, and increases the proliferative index in thymus tissue (from 26% to 37% in studies). The peptide modulates tyrosine phosphorylation of mitogen-activated cytoplasmic kinases and helps rejuvenate aged immune systems by restoring proper gene expression patterns.

Key Benefits

  • Increases mean lifespan 20-40% in animal models
  • Suppresses tumor development
  • Stimulates thymocyte proliferation
  • Activates T-helper cells
  • Restores chromatin structure in aged lymphocytes
  • Enhances intestinal barrier function
  • Improves enzyme activity in aged tissue
  • Part of comprehensive longevity protocols

Quick Stats

Typical Dose
10-20 mg per day (oral capsules) or 10 mg (injectable)
Frequency
Daily for 10-20 consecutive days (Khavinson bioregulator cycle)
Cycle Duration
10-20 day cycle (typical 10 days in research)
Storage
Oral capsules: room temperature; Lyophilized powder/reconstituted: 2-8°C refrigerated

Molecular Information

Molecular Weight
275 Da
Length
2 amino acids
Type
Dipeptide bioregulator
Half-Life
Not established

Amino Acid Sequence

One-letter: KE
Lys
1

Lysine

Position 1

Glu
2

Glutamic Acid

Position 2

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Thymus Rejuvenation

Effective

Stimulates thymocyte proliferation and enlarges thymic lobules.

T-Cell Activation

Effective

Activates T-helper cells and improves immune response.

Age-Related Immune Decline

Effective

Restores chromatin structure and gene expression in aged lymphocytes.

Lifespan Extension

Effective

Long-term treatment increased mean lifespan 20-40% in rodent studies.

Tumor Suppression

Moderate

Suppresses development of spontaneous and induced tumors.

Tissue Regeneration

Moderate

Promotes recovery in tissues exposed to radiation damage.

Intestinal Function

Moderate

Restores brush border membrane enzyme levels in aged animals.

Barrier Function

Moderate

Enhances intestinal barrier function in aged rats.

Dosing Protocols

oral

Available in capsule form for oral administration. As the shortest Khavinson peptide (just 2 amino acids), Vilon is easily absorbed orally. Typical protocol involves 10-20 day cycles, repeated 2-3 times per year.

Goal Dose Frequency Route
Standard protocol 10-20 mg Daily for 10-20 days Oral capsules
Maintenance 10 mg 2-3 cycles yearly Oral capsules

Key Tips

  • Convenient oral administration
  • Excellent GI absorption as dipeptide
  • Room temperature storage for capsules

injectable

Injectable form available for direct administration.

Goal Dose Frequency Route
Research protocol 10 mg Daily for 10 days IM or SubQ

Key Tips

  • Direct absorption
  • Precise dosing
Materials Needed
Bacteriostatic water Insulin syringes Alcohol swabs Sterile vial
Steps
  1. 1 Clean work area thoroughly
  2. 2 Reconstitute with appropriate volume
  3. 3 Gently swirl until dissolved
  4. 4 Store reconstituted solution refrigerated

Peptide Interactions

Thymalin

Synergistic

Both target thymus/immune system; complementary mechanisms.

Epitalon

Synergistic

Often combined in comprehensive anti-aging Khavinson protocols.

Crystagen

Synergistic

Both have immunoprotecting properties; different mechanisms.

Thymogen

Compatible

Related immune peptides; can be used in comprehensive protocols.

What to Expect

During cycle

Immune activation and gene expression modulation begins

Post-cycle

Effects persist due to epigenetic changes

Weeks-Months

Immune function improvements

Long-term

Cumulative benefits; longevity effects in animal models

Side Effects & Safety

Common Side Effects

  • Generally well-tolerated
  • Minimal side effects reported

Stop Signs

  • Allergic reactions
  • Unusual immune symptoms

Contraindications

  • Active autoimmune flares (consult physician)
  • Known hypersensitivity
  • Pregnancy or breastfeeding

Quality Checklist

Good Signs

  • White powder or capsules
  • Clear solution if reconstituted
  • Proper packaging and labeling

Warning Signs

  • Unknown source or purity

Bad Signs

  • Discoloration
  • Unusual odor
  • Damaged packaging

Research & References

Key References

  1. 2003

    Peptide Bioregulators Increase Lifespan

    Biogerontology

    Long-term treatment with peptide preparations including Vilon increased mean lifespan 20-40% and suppressed tumorigenesis.

  2. 2002

    Vilon Effects on Aged Lymphocytes

    Bulletin of Experimental Biology and Medicine

    Vilon improved lymphocytes from old people by restoring chromatin structure and gene expression.

  3. 2022

    Peptides Regulating Proliferative Activity in THP-1 Cells

    PMC

    Vilon and other Khavinson peptides modulate key proliferative patterns and tyrosine phosphorylation of kinases.

  4. 2018

    Short Peptide Immunoprotecting Properties

    Advances in Gerontology

    Vilon and related peptides possess age-associated immunoprotecting properties in the spleen.

Search PubMed for Vilon

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