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Semaglutide Price Comparison

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60 results
30 suppliers · 13 dosages · 60 products
Best Price
Save 86%
Vionex Peptides logo
Vionex Peptides

Semaglutide 10mg

In Stock 10mg Lab Tested
£19.99
FREE delivery
Astra Labs logo
Astra Labs

Semaglutide 5mg

£21.99
In Stock 5mg Lab Tested
Save 77% FREE delivery
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Core Peptides

Semaglutide 2mg

£28.08
In Stock 2mg Lab Tested
FREE delivery
Unavailable
Raccoon Peptides logo
★ 5.0
Raccoon Peptides

Semaglutide 5mg

£29.00
In Stock 5mg Lab Tested
Save 69% FREE delivery
Raccoon Peptides logo
★ 5.0
Raccoon Peptides

Semaglutide 5mg

£29.00
In Stock 5mg Lab Tested
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Blue Peak Peptides

Semaglutide

£29.95
In Stock 10mg Lab Tested
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Certa Peptides

Semaglutide 5mg

£29.99
In Stock 5mg Lab Tested
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Astra Labs

Semaglutide 10mg

£29.99
In Stock 10mg Lab Tested
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Ideal Labz

Semaglutide 5mg

£34.90
In Stock 5mg Lab Tested
Save 63% FREE delivery
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Orbitrex Peptides

Semaglutide 5mg

£39.99
In Stock 5mg Lab Tested
Save 58% FREE delivery
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CMSR Labs

Semaglutide 5mg

£44.95
In Stock 5mg
Save 53% FREE delivery
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Buy Reta EU

Semaglutide 15mg

£45.00
In Stock 15mg
Save 65% FREE delivery
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Pondok Peptides

Semaglutide 15mg

£48.00
In Stock 15mg
Save 63% FREE delivery
Raccoon Peptides logo
★ 5.0
Raccoon Peptides

Semaglutide 10mg

£49.00
In Stock 10mg Lab Tested
Save 65% FREE delivery
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Pen Peptide

Semaglutide 1mg

£49.00
In Stock 1mg Pen
FREE delivery
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Ideal Labz

Semaglutide 10mg

£49.90
In Stock 10mg Lab Tested
Save 64% FREE delivery
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Nova Peptides

Semaglutide 10mg

£50.00
In Stock 10mg Lab Tested
Save 64% + £5.00 delivery
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Astra Labs

Semaglutide 20mg

£54.99
In Stock 20mg Lab Tested
Save 66% FREE delivery
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Peptides Lab UK

Semaglutide 5mg

£59.00
In Stock 5mg Lab Tested
Save 38% FREE delivery
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Bio Peptides UK

Semaglutide

£59.00
In Stock 10mg Lab Tested
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Peptagenix Peptides

Semaglutide 5mg

£60.00
In Stock 5mg Lab Tested
Save 37% FREE delivery
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Power Peptides

Semaglutide 10mg

£60.00
In Stock 10mg
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ProLab Peptides

Semaglutide 10mg

£62.99
In Stock 10mg
Save 55% FREE delivery
Global Peptides logo
Global Peptides

Semaglutide 20mg

£64.99
In Stock 20mg
Save 59% FREE delivery
Apex Receptor logo
★ 1.8
Apex Receptor

Semaglutide 5mg

£65.00
In Stock 5mg Lab Tested
Save 32% FREE over £50
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Wholesale Peptides

Semaglutide 50mg

£65.00
In Stock 50mg
FREE delivery
Raccoon Peptides logo
★ 5.0
Raccoon Peptides

Semaglutide 20mg

£69.00
In Stock 20mg Lab Tested
Save 57% FREE delivery
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UK Peptide Shop

Semaglutide 5mg

£69.99
In Stock 5mg
Save 26% FREE delivery
Unavailable
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Genetic Research

Semaglutide 10mg

£69.99
In Stock 10mg Lab Tested
Save 50% FREE delivery
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Orbitrex Peptides

Semaglutide 10mg

£69.99
In Stock 10mg Lab Tested
Save 50% FREE delivery
Vitality Peptides logo
★ 4.7
Vitality Peptides

Semaglutide 5mg

£70.90
In Stock 5mg Lab Tested
Save 25% FREE delivery
Unavailable
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Vionex Peptides

Semaglutide 5mg

£70.90
In Stock 5mg Lab Tested
Save 25% FREE delivery
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Pro Peptides Plus

Semaglutide 5mg

£74.99
In Stock 5mg
Save 21% FREE delivery
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CMSR Labs

Semaglutide 10mg

£76.95
In Stock 10mg
Save 45% FREE delivery
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Precision Peptides

Semaglutide 20mg

£80.00
In Stock 20mg Lab Tested
Save 50% FREE delivery
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Wholesale Peptides

Semaglutide 100mg

£80.00
In Stock 100mg
FREE delivery
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CMSR Labs

Semaglutide 15mg

£84.95
In Stock 15mg
Save 35% FREE delivery
UK Peptide Shop logo
UK Peptide Shop

Semaglutide 10mg

£84.99
In Stock 10mg
Save 39% FREE delivery
Unavailable
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Alpha Peptides

Semaglutide 10mg

£85.00
In Stock 10mg
Save 39% FREE delivery
Bio Peptides UK logo
Bio Peptides UK

Semaglutide

£89.00
In Stock 20mg Lab Tested
Save 44% FREE delivery
Biopro Store logo
Biopro Store

Semaglutide 5mg

£95.00
In Stock 5mg Pen
FREE delivery
Pen Peptide logo
Pen Peptide

Semaglutide 5mg

£95.00
In Stock 5mg Pen
FREE delivery
Power Peptides logo
Power Peptides

Semaglutide 20mg

£97.50
In Stock 20mg
Save 39% FREE delivery
Adaptog Research logo
Adaptog Research

Semaglutide 8mg

£99.00
In Stock 8mg Pen
Save 24% FREE delivery
Ideal Labz logo
Ideal Labz

Semaglutide 20mg

£99.90
In Stock 20mg Lab Tested
Save 38% FREE delivery
CMSR Labs logo
CMSR Labs

Semaglutide 20mg

£99.95
In Stock 20mg
Save 38% FREE delivery
Peptagenix Peptides logo
Peptagenix Peptides

Semaglutide 10mg

£100.00
In Stock 10mg Lab Tested Pen
Save 29% FREE delivery
Vitality Peptides logo
★ 4.7
Vitality Peptides

Semaglutide 10mg

£100.40
In Stock 10mg Lab Tested
Save 28% FREE delivery
Unavailable
UK Peptide Shop logo
UK Peptide Shop

Semaglutide 20mg

£104.99
In Stock 20mg
Save 34% FREE delivery
Unavailable
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Peptides 4U

Semaglutide 30mg

£110.00
In Stock 30mg Lab Tested
FREE delivery
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Nova Peptides

Semaglutide 30mg

£110.00
In Stock 30mg Lab Tested
+ £5.00 delivery
Wholesale Peptides logo
Wholesale Peptides

Semaglutide 150mg

£110.00
In Stock 150mg
FREE delivery
Orbitrex Peptides logo
Orbitrex Peptides

Semaglutide 20mg

£119.99
In Stock 20mg Lab Tested
Save 25% FREE delivery
Wholesale Peptides logo
Wholesale Peptides

Semaglutide 20mg

£130.00
In Stock 20mg
Save 19% FREE delivery
Biopro Store logo
Biopro Store

Semaglutide 8mg

£130.00
In Stock 8mg Pen
FREE delivery
Alpha Peptides logo
Alpha Peptides

Semaglutide 15mg

£130.00
In Stock 15mg
FREE delivery
Wholesale Peptides logo
Wholesale Peptides

Semaglutide 200mg

£130.00
In Stock 200mg
FREE delivery
Biopro Store logo
Biopro Store

Semaglutide 10mg

£140.00
In Stock 10mg
FREE delivery
Alpha Peptides logo
Alpha Peptides

Semaglutide 20mg

£160.00
In Stock 20mg
FREE delivery
Wholesale Peptides logo
Wholesale Peptides

Semaglutide 300mg

£160.00
In Stock 300mg
FREE delivery

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Semaglutide Profile

Fda Approved FDA Approved

GLP-1 Receptor Agonist | Weight Loss & Diabetes

Overview

Long-acting GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management. Over 17,000 trial participants have demonstrated significant efficacy through appetite suppression and glycemic control. The 7-day half-life enables convenient weekly dosing.

Mechanism of Action

Mimics native GLP-1, binding to receptors to stimulate glucose-dependent insulin secretion, suppress glucagon, slow gastric emptying, and reduce appetite via hypothalamic pathways.

Key Benefits

  • 15-20% average body weight reduction
  • Established cardiovascular protection
  • Convenient once-weekly dosing options
  • Comprehensive safety data from extensive trials
  • Flexible injectable and oral formulations

Quick Stats

Typical Dose
0.25mg starting, titrate to 1-2.4mg weekly
Frequency
Once weekly (same day each week)
Cycle Duration
Ongoing therapy as prescribed
Storage
Pen: 2-8°C before first use, room temp up to 56 days after. Compounded: 2-8°C

Molecular Information

Molecular Weight
4,113.64 Da
Length
31 amino acids
Type
GLP-1 receptor agonist
Half-Life
~7 days (168 hours)

Amino Acid Sequence

One-letter: HUEGTFTSDVSSYLEGQAAKEFIAWLVRGRG
His
1

Histidine

Position 1

Aib
2

Aminoisobutyric Acid

Position 2

Glu
3

Glutamic Acid

Position 3

Gly
4

Glycine

Position 4

Thr
5

Threonine

Position 5

Phe
6

Phenylalanine

Position 6

Thr
7

Threonine

Position 7

Ser
8

Serine

Position 8

Asp
9

Aspartic Acid

Position 9

Val
10

Valine

Position 10

Ser
11

Serine

Position 11

Ser
12

Serine

Position 12

Tyr
13

Tyrosine

Position 13

Leu
14

Leucine

Position 14

Glu
15

Glutamic Acid

Position 15

Gly
16

Glycine

Position 16

Gln
17

Glutamine

Position 17

Ala
18

Alanine

Position 18

Ala
19

Alanine

Position 19

Lys
20

Lysine

Position 20

Glu
21

Glutamic Acid

Position 21

Phe
22

Phenylalanine

Position 22

Ile
23

Isoleucine

Position 23

Ala
24

Alanine

Position 24

Trp
25

Tryptophan

Position 25

Leu
26

Leucine

Position 26

Val
27

Valine

Position 27

Arg
28

Arginine

Position 28

Gly
29

Glycine

Position 29

Arg
30

Arginine

Position 30

Gly
31

Glycine

Position 31

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

Acylated with C18 fatty diacid via γ-Glu spacer

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Clinically Significant Weight Reduction

Most Effective

FDA-approved for chronic weight management with average 15-20% body weight loss in clinical trials.

Appetite and Craving Control

Most Effective

Reduces hunger and food cravings through central nervous system GLP-1 receptor activation.

Sustained Weight Maintenance

Effective

Long-term studies show maintained weight loss with continued treatment over 2+ years.

Glycemic Control

Most Effective

FDA-approved for type 2 diabetes with HbA1c reductions of 1.5-2% in clinical trials.

Cardiovascular Protection

Most Effective

Proven 26% reduction in cardiovascular death, MI, or stroke in high-risk diabetes patients.

Beta Cell Preservation

Effective

Improves insulin secretion and may preserve pancreatic beta cell function.

Metabolic Syndrome Improvement

Effective

Addresses multiple components: weight, glucose, blood pressure, and lipids.

NASH/Fatty Liver

Moderate

Emerging evidence for improvements in non-alcoholic fatty liver disease.

Inflammation Reduction

Moderate

Decreases systemic inflammation markers independent of weight loss.

Dosing Protocols

injectable

Pre-filled pen devices for once-weekly subcutaneous injection. Brands include Ozempic (diabetes) and Wegovy (weight loss).

Goal Dose Frequency Route
Weight Loss Initiation 0.25mg Weekly x 4 weeks, then increase Subcutaneous
Weight Loss Maintenance 2.4mg Weekly (after 16-week titration) Subcutaneous
Diabetes Management 0.5-1mg Weekly Subcutaneous
Cardiovascular Protection 0.5-1mg Weekly Subcutaneous
Tolerability-Based 0.25-2.4mg Weekly (individualized) Subcutaneous

Key Tips

  • Once-weekly dosing
  • Abdomen, thigh, or upper arm injection sites
  • Pre-filled pens available
Materials Needed
Semaglutide pre-filled pen or vial Pen needles (if using pen device) Alcohol swabs Sharps disposal container Injection site rotation chart
Steps
  1. 1 If using pre-filled pen, attach new needle and prime per instructions
  2. 2 If using vial, draw prescribed dose with appropriate syringe
  3. 3 Clean injection site with alcohol swab and let dry
  4. 4 Inject subcutaneously at 90-degree angle (45-degree if lean)
  5. 5 Hold for 6 seconds after injection to ensure full dose delivery
  6. 6 Dispose of needle safely and rotate injection sites weekly

oral

Rybelsus tablets use SNAC technology for enhanced absorption. Requires strict administration protocol.

Goal Dose Frequency Route
Diabetes Initiation 3mg Daily x 30 days Oral (empty stomach)
Standard Diabetes Dose 7mg Once daily Oral (empty stomach)
Maximum Diabetes Dose 14mg Once daily Oral (empty stomach)

Key Tips

  • No injection required
  • Daily dosing maintains consistent levels
  • SNAC technology enhances absorption
Materials Needed
Rybelsus tablets (3mg, 7mg, or 14mg) Plain water only (maximum 4 ounces/120mL) Timer or alarm for 30-minute wait
Steps
  1. 1 Take first thing in morning on completely empty stomach
  2. 2 Swallow tablet whole with no more than 4 ounces plain water
  3. 3 Do not crush, chew, or split tablet
  4. 4 Wait at least 30 minutes before eating, drinking, or taking other medications
  5. 5 After 30 minutes, resume normal activities and meals
  6. 6 Take at same time each day for consistency

Peptide Interactions

Insulin

Monitor

May increase hypoglycemia risk when combined; requires blood glucose monitoring.

Tirzepatide

Avoid

Both are incretin mimetics with overlapping mechanisms; concurrent use increases side effects.

Cagrilintide

Synergistic

Combined as CagriSema in clinical trials for enhanced weight loss efficacy.

Metformin

Compatible

Commonly used together for diabetes management with good safety profile.

BPC-157

Compatible

No contraindications; may help with GI side effects.

Sulfonylureas

Monitor

Increased hypoglycemia risk; may require sulfonylurea dose reduction.

Oral Medications

Requires Timing

Delayed gastric emptying may affect absorption of oral medications.

What to Expect

Week 1-4

Mild appetite reduction, possible nausea during initial dose

Month 2-3

Noticeable weight loss (5-10% typical), improved satiety

Month 4-6

Continued weight loss (10-15% common), stable glucose levels

Month 6+

Weight loss plateau possible, focus on maintenance

Diabetes

Blood sugar improvements within 1-2 weeks

Side Effects & Safety

Common Side Effects

  • Nausea
  • Diarrhea
  • Vomiting
  • Constipation
  • Abdominal pain

Monitoring

  • Blood glucose levels
  • Signs of pancreatitis
  • Thyroid nodules
  • Kidney function

Stop Signs

  • Severe persistent abdominal pain (possible pancreatitis)
  • Persistent vomiting preventing fluid intake
  • Signs of thyroid tumor (neck lump, hoarseness, trouble swallowing)
  • Severe allergic reaction (rash, itching, difficulty breathing)
  • Vision changes (possible diabetic retinopathy progression)
  • Severe hypoglycemia (if combined with insulin/sulfonylureas)
  • Kidney problems (decreased urination, swelling)

Contraindications

  • Personal or family history of medullary thyroid cancer
  • Multiple Endocrine Neoplasia syndrome type 2 (MEN 2)
  • Pregnancy or breastfeeding
  • History of pancreatitis

Quality Checklist

Good Signs

  • FDA-approved branded products (Ozempic, Wegovy, Rybelsus)
  • Proper refrigeration verified and not expired
  • Clear, colorless to slightly yellow solution in pen/vial

Warning Signs

  • Compounded versions - FDA warns about untested compounded semaglutide

Bad Signs

  • Cloudy or discolored solution
  • Particles or precipitation visible
  • Non-pharmacy sources or unverified online sellers

Research & References

Key References

2021

STEP 1 Trial - Weight Management

1,961 participants participants

14.9% average weight loss versus 2.4% with placebo over 68 weeks with 2.4mg weekly.

2023

SELECT Cardiovascular Outcomes

17,604 participants participants

20% reduction in major adverse cardiovascular events over 5 years with 2.4mg weekly.

2016-2019

SUSTAIN Diabetes Program

Average HbA1c reductions of 1.5-1.8% across multiple trials.

2022

STEP 5 Two-Year Maintenance

304 participants participants

Sustained weight loss of 15.2% at week 104 with 2.4mg weekly.

2019

PIONEER Oral Semaglutide

9,543 participants participants

Oral efficacy comparable to injectable formulations at 3-14mg daily.

2022

STEP TEENS Adolescent Study

201 adolescents (12-17 years) participants

16.1% BMI reduction in adolescent population over 68 weeks.

Research Library

Semaglutide research & guides

Plain-English guides and study summaries from published literature.

View all 2
GLP-1s Aren’t Miracle Drugs—or Metabolism Killers Guides 7 min

GLP-1s Aren’t Miracle Drugs—or Metabolism Killers

Most guys hear “GLP-1” and immediately land in one of two camps: Camp 1: “It’s a miracle drug that melts fat with zero downside.” Camp 2: “It’ll destroy your body—lose muscle, wreck your metabolism, end up frail.”

Read article
Semaglutide: is it the right tool for you, or is there a better option now? Guides 6 min

Semaglutide: is it the right tool for you, or is there a better option now?

Semaglutide works because it makes a calorie deficit easier to sustain. It suppresses appetite, slows gastric emptying, and helps you feel full longer. But it doesn’t burn fat directly, it can come with a real lean-mass loss problem, and a lot of people regain weight after stopping unless they use that appetite-suppression window to build habits. And if your real goal is fat loss and body composition, there are newer options that generally perform better.

Read article

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