GHK-Cu Price Comparison

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Best Price £9.99
Average £27.79
Highest £53.99
You Could Save 81%
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BioPlex Peptides logo
★ 5.0
BioPlex Peptides

Snap-8 10mg & GHK-cu 100mg

£53.99
95 /100 Confidence In Stock 10mg Lab Tested
FREE delivery
Lucid Peptides logo

GHK-Cu 10mg

£17.95
77 /100 Confidence In Stock 10mg
Save 67% FREE delivery
Best Price
Save 81%
UK Chems logo
UK Chems 50 /100 Confidence

GHK-Cu 10mg

Out of Stock 10mg
£9.99
+ £9.99 delivery
Nupex logo

GHK-Cu 10mg

£13.25
50 /100 Confidence In Stock 10mg Lab Tested
Save 75% FREE delivery
Peptide Shop logo

GHK-Cu 10mg

£17.00
50 /100 Confidence In Stock 10mg
Save 69% FREE delivery
Rhythm Peptides logo

GHK-Cu 10mg

£19.99
50 /100 Confidence In Stock 10mg Lab Tested
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Nicello UK logo

GHK-Cu 10mg

£27.95
50 /100 Confidence In Stock 10mg
Save 48% + £9.99 delivery
Biolabshopuk logo

GHK-Cu 10mg

£44.99
50 /100 Confidence In Stock 10mg
Save 17% FREE delivery
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Biolabshopofficial logo

GHK-Cu + Epithalon mix 20/10mg

£44.99
50 /100 Confidence In Stock 10mg
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GHK-Cu Profile

Well Studied

Copper Peptide | Skin Regeneration & Anti-Aging Compound

Overview

Naturally occurring copper tripeptide found in human plasma, saliva, and urine. GHK-Cu affects 31.2% of human genes and declines significantly with age—from ~200 ng/ml at age 20 to ~80 ng/ml at age 60. Known for exceptional skin regeneration, wound healing, and anti-aging properties.

Mechanism of Action

Penetrates skin layers, activates fibroblasts, stimulates collagen and elastin synthesis, promotes angiogenesis, and modulates inflammatory responses. The copper ion is essential for enzyme cofactor activity in tissue repair processes.

Key Benefits

  • Enhanced collagen production (70% increase in type I and III)
  • Improved skin elasticity
  • Reduced fine lines and wrinkles
  • Accelerated wound healing
  • Hair growth stimulation
  • Antioxidant protection

Quick Stats

Typical Dose
0.5-2% topical or 1-3mg injectable
Frequency
1-2x daily
Cycle Duration
8-16 weeks
Storage
Room temperature (topical) or 2-8°C (injectable)

Molecular Information

Molecular Weight
404.96 Da
Length
3 amino acids
Type
Copper tripeptide
Half-Life
0.5-2 hours

Amino Acid Sequence

One-letter: GHK
Gly
1

Glycine

Position 1

His
2

Histidine

Position 2

Lys
3

Lysine

Position 3

N-terminus C-terminus
Hydrophobic
Polar
Positive (+)
Negative (-)
Modified

Modifications

Complexed with copper (Cu2+) for enhanced bioavailability

Research Indications

The following information is derived from published scientific literature and is provided for educational and research reference purposes only. It does not constitute medical advice, diagnosis, or treatment recommendations. These peptides are not approved for human use and are sold exclusively for in-vitro laboratory research.

Collagen Synthesis

Most Effective

Increases type I and III collagen production by up to 70% in human dermal fibroblasts.

Elastin Production

Most Effective

Stimulates elastin synthesis for improved skin elasticity and resilience.

Skin Barrier Function

Effective

Strengthens protective barrier and improves moisture retention.

Follicle Stimulation

Effective

Promotes hair follicle enlargement and extends anagen (growth) phase.

Scalp Health

Effective

Improves scalp circulation and reduces inflammation.

Immune Modulation

Moderate

Regulates inflammatory cytokine production.

Tissue Protection

Moderate

Protects tissues from oxidative stress and damage.

Dosing Protocols

topical

Most common delivery method for skin and hair applications. Available as creams, serums, and solutions.

Goal Dose Frequency Route
Anti-aging skincare 0.5-1% cream 1-2x daily Topical application
Hair growth stimulation 1-2% solution 1x daily Scalp massage
Wound healing 1-2% gel 2-3x daily Direct application
General skin health 0.5% serum 1x daily Face and neck
Intensive repair 2% cream 1x daily Targeted areas

Key Tips

  • Non-invasive application
  • Targeted delivery to skin
  • Room temperature storage
Steps
  1. 1 Cleanse skin thoroughly with gentle cleanser
  2. 2 Pat skin dry and wait 5 minutes
  3. 3 Apply thin, even layer to target areas
  4. 4 Massage gently until fully absorbed (1-2 minutes)
  5. 5 Follow with moisturizer if using serum
  6. 6 Always apply sunscreen during daytime use

injectable

Injectable form provides systemic effects but is not FDA-approved. Requires refrigeration after reconstitution.

Goal Dose Frequency Route
Systemic anti-aging 1-2mg 1x daily SubQ
Enhanced regeneration 2-3mg 1-2x daily SubQ

Key Tips

  • Systemic delivery
  • Higher bioavailability than topical
Materials Needed
GHK-Cu lyophilized powder vial Bacteriostatic water (BAC water) Insulin syringes (29-31 gauge) Alcohol swabs Sterile work surface
Steps
  1. 1 Allow vial to reach room temperature (15-20 minutes)
  2. 2 Clean vial tops with alcohol swabs
  3. 3 Draw calculated BAC water into syringe
  4. 4 Inject slowly down vial side
  5. 5 Gently swirl until fully dissolved (light blue color is normal)
  6. 6 Store reconstituted solution at 2-8°C, use within 30 days

Peptide Interactions

BPC-157

Synergistic

Complementary tissue healing and regeneration pathways.

TB-500

Synergistic

Enhanced wound healing and tissue repair when combined.

Melanotan II

Monitor

Both affect melanin production; use caution when combining.

Copper Supplements

Avoid

Risk of copper toxicity; do not combine with oral copper supplements.

CJC-1295

Compatible

No known interactions.

Iron Chelators

Monitor

May affect copper absorption and activity.

What to Expect

Week 1-2

Improved skin texture and hydration

Week 3-4

Reduction in fine lines and increased skin smoothness

Week 6-8

Enhanced skin firmness and elasticity

Week 8-12

Visible improvement in skin tone and clarity

Hair Growth

6-12 weeks for initial results

Side Effects & Safety

Common Side Effects

  • Mild skin irritation initially (usually resolves)
  • Increased photosensitivity

Monitoring

  • Patch test before first use
  • Avoid contact with eyes and mucous membranes

Stop Signs

  • Severe skin irritation, burning, or persistent redness
  • Allergic reactions (rash, swelling, difficulty breathing)
  • Unusual skin discoloration or staining
  • Persistent metallic taste (injectable)
  • Worsening of skin condition after 4-6 weeks

Contraindications

  • Known copper sensitivity or Wilson's disease
  • Active skin infections at application site
  • Pregnancy or breastfeeding (injectable)

Quality Checklist

Good Signs

  • Light blue tint from copper content
  • Smooth texture, non-gritty
  • Stable formulation without separation or crystallization
  • Professional packaging with UV protection

Warning Signs

  • Slight color variation acceptable within blue spectrum

Bad Signs

  • Green or dark discoloration (oxidation/contamination)
  • Grainy texture (poor formulation or crystallization)
  • Separation or settling of components

Research & References

Key References

  1. 1980

    Growth-modulating plasma tripeptide may function by facilitating copper uptake into cells. PubMed

    Nature · Pickart L, Freedman JH, Loker WJ, Peisach J, Perkins CM, Stenkamp RE, Weinstein B

    This study reported that the human plasma tripeptide glycyl-L-histidyl-L-lysine forms a copper complex and examined its association with cellular copper uptake and growth-modulating activity.

  2. 1988

    Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. PubMed

    FEBS letters · Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP

    This fibroblast-culture study reported increased collagen synthesis after exposure to the glycyl-L-histidyl-L-lysine-Cu2+ complex.

  3. 1992

    Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+. PubMed

    Life sciences · Wegrowski Y, Maquart FX, Borel JP

    This cell-culture study reported that glycyl-L-histidyl-L-lysine-Cu2+ was associated with increased sulfated glycosaminoglycan synthesis by fibroblasts.

  4. 2000

    The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. PubMed

    Life sciences · Siméon A, Emonard H, Hornebeck W, Maquart FX

    This fibroblast-culture study reported increased matrix metalloproteinase-2 expression in response to the glycyl-L-histidyl-L-lysine-Cu2+ complex.

  5. 2018

    Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. PubMed

    International journal of molecular sciences · Pickart L, Margolina A

    This review discussed gene-expression datasets and experimental literature relating GHK-Cu to extracellular-matrix regulation, antioxidant-associated pathways, and tissue-remodeling biology.

Search PubMed for GHK-Cu

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