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KPV
KPV
KPV - 10mg
KPV
KPV
KVP 10mg (KPV Tripeptide)
KPV
KPV 10mg
KPV
KPV
KPV 10mg
KPV 10mg
KPV 10mg
KPV 10mg
Compare 125 prices for KPV. Cheapest: £15.99. Average: £37.10.
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| £25.00 | £2.50/mg | In Stock | Free over £100 |
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| £18.99 | £1.90/mg | Out of Stock | Free |
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| £25.00 | £2.50/mg | In Stock | Free over £100 |
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| £44.99 | £4.50/mg | In Stock | Free |
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| £24.99 | £2.50/mg | In Stock | Free over £100 |
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| £29.99 | £3.00/mg | In Stock | Free |
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| £24.00 | £2.40/mg | In Stock | Free over £100 |
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| £15.99 | £1.60/mg | In Stock | Free |
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| £25.00 | £2.50/mg | In Stock | Free over £50 |
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| £19.00 | £1.90/mg | In Stock | Free |
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| £30.00 | £3.00/mg | In Stock | Free |
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| £17.99 | £1.80/mg | Out of Stock | Free over £150 |
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| £30.00 | £3.00/mg | In Stock | Free |
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| £33.40 | £3.34/mg | In Stock | Free |
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| £19.99 | £2.00/mg | In Stock | Free over £75 |
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| £27.99 | £2.80/mg | In Stock | Free over £150 |
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| £28.00 | £2.80/mg | In Stock | Free |
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| £23.99 | £2.40/mg | In Stock | Free over £75 |
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| £24.50 | £2.45/mg | In Stock | Free over £30 |
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| £19.97 | £2.00/mg | In Stock | Free |
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| £29.99 | £3.00/mg | In Stock | Free |
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| £23.95 | £2.40/mg | In Stock | Free |
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| £24.99 | £2.50/mg | In Stock | £9.99 |
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| £23.99 | £2.40/mg | In Stock | Free |
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| £23.99 | £2.40/mg | In Stock | Free |
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Anti-Inflammatory Tripeptide | Alpha-MSH Fragment
KPV is a potent anti-inflammatory tripeptide derived from the C-terminal of alpha-MSH. It exhibits remarkable anti-inflammatory and antimicrobial properties without the pigmentation effects of full α-MSH, making it ideal for inflammation management.
Enters cells and inhibits inflammatory pathways at the nuclear level, particularly NF-κB signaling. Reduces pro-inflammatory cytokines (TNF-α, IL-6) without causing immunosuppression like steroids.
Reduces TNF-α and IL-6 through NF-κB pathway inhibition.
May help balance overactive immune responses in autoimmune conditions.
Potential benefits for inflammatory arthritis through cytokine reduction.
Demonstrated benefit in Crohn's disease and ulcerative colitis models.
Helps restore intestinal barrier function.
Selective antimicrobial activity preserves beneficial gut bacteria.
Topical KPV reduced psoriatic markers by 60% and improved skin barrier function.
Reduces inflammatory skin conditions without systemic effects.
Subcutaneous injection provides systemic anti-inflammatory effects. Abdomen is preferred for gut-related issues.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| General anti-inflammatory | 200-300mcg | Once daily | SubQ |
| Active inflammation | 250mcg | Twice daily | SubQ |
| Autoimmune support | 500mcg | Once daily | SubQ |
| Acute flare-ups | 500mcg | 2x daily for 1 week, then reduce | SubQ |
Oral administration provides direct gut exposure for intestinal conditions.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Gut health support | 200-500mcg | 2-3x daily | Mix in water/juice or enteric capsules |
Topical cream/gel for localized skin inflammation without systemic absorption.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Skin inflammation | 0.1-0.5% cream/gel | 2-3x daily | Affected skin areas |
Nasal spray with limited data. May provide systemic effects through nasal absorption.
| Goal | Dose | Frequency | Route |
|---|---|---|---|
| Systemic anti-inflammatory | 100-300mcg | 2-3x daily (1-2 sprays per nostril) | Nasal spray |
Enhanced gut healing and anti-inflammatory effects through complementary mechanisms.
Different mechanisms; can be combined safely.
Complementary antimicrobial and healing effects.
Both support immune function through different pathways.
Synergistic for skin health and regeneration.
Both are α-MSH related; KPV lacks pigmentation effects but monitor for cumulative effects.
Subtle reduction in inflammation, improved energy
Noticeable decrease in inflammatory symptoms
Improved gut function (if applicable), reduced pain/swelling
Significant improvement in inflammatory markers
Sustained benefits, improved quality of life
Drug Delivery Research
Enhanced delivery methods using nanoparticle technology.
Gut Health Journal
KPV combined with probiotics for enhanced IBS treatment.
Inflammation Research
Potential application in post-COVID inflammatory conditions.
TheScientificWorldJournal · Catania A, Lonati C, Sordi A, Carlin A, Leonardi P, Gatti S
This review summarized anti-inflammatory mechanisms of melanocortin peptides and discussed KPV as the C-terminal alpha-MSH tripeptide with activity in cellular and animal inflammation models.
Plain-English guides and study summaries from published literature.
Guides
5 min
KPV is regularly mentioned in peptide conversations around inflammation and vascular health. Here is a clear, balanced look at why it attracts attention and how it is typically framed in relation to endothelial function and immune regulation.
Read article
Guides
6 min
Conversations around cardiovascular health often focus on cholesterol, but many peptide discussions place equal emphasis on inflammation, endothelial function and tissue repair. Here is a balanced look at why KPV and TB-500 are being explored in that context.
Read article
Guides
4 min
Introduction to KPV KPV is the smart bomb. It’s a tripeptide—three amino acids in a precise sequence: Lysine Proline Valine It’s not some synthetic alien molecule. It’s a fragment—a surgical piece—of a naturally occurring hormone in your body called alpha-MSH (alpha melanocyte-stimulating hormone). Alpha-MSH has broad jobs: inflammation control, pigmentation, and energy homeostasis. Think of alpha-MSH as the entire command structure. KPV is the special operations unit.
Read article
Guides
4 min
What KPV actually is KPV is a tripeptide: Lysine – Proline – Valine. That’s it. Three amino acids. And that’s the first thing people get wrong: they hear “three amino acids” and assume “small = minor.” No. Small means fast, targeted, and built for signaling. KPV isn’t a poison. It isn’t random. It’s not a “foreign drug” your body has to tolerate. It’s part of your internal control system—your body’s way of saying: “Inflammation served its purpose. Now shut it down and start repairing.”
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